Mouse Anti-Morphine Recombinant Antibody (clone 9B1) (CAT#: PABZ-087)
Recombinant mouse antibody (9B1) is capable of binding to Morphine. The binding site of the anti-morphine antibody 9B1 is topologically a depression on the protein surface rather than a pocket.
Specific Inquiry
![Figure 1 Saturation binding of 9B1 with 2 nM [H3]-morphine.](https://img.creativebiolabs.net/productimages/PD-PABZ-087-1.jpg)
Figure 1 Saturation binding of 9B1 with 2 nM [H3]-morphine.
Zhang, C. H., Kim, K., Jin, Z., Zheng, F., & Zhan, C. G. (2020). Systematic Structure-Based Virtual Screening Approach to Antibody Selection and Design of a Humanized Antibody against Multiple Addictive Opioids without Affecting Treatment Agents Naloxone and Naltrexone. ACS chemical neuroscience, 12(1), 184-194.
![Figure 2 Saturation binding of h9B1 with 2 nM [H3]-morphine.](https://img.creativebiolabs.net/productimages/PD-PABZ-087-2.jpg)
Figure 2 Saturation binding of h9B1 with 2 nM [H3]-morphine.
Zhang, C. H., Kim, K., Jin, Z., Zheng, F., & Zhan, C. G. (2020). Systematic Structure-Based Virtual Screening Approach to Antibody Selection and Design of a Humanized Antibody against Multiple Addictive Opioids without Affecting Treatment Agents Naloxone and Naltrexone. ACS chemical neuroscience, 12(1), 184-194.
![Figure 3 Competitive binding of 2 nM [H3]-morphine against 6-MAM (D), heroin (E) and hydrocodone (F) with 9B1 (20 nM).](https://img.creativebiolabs.net/productimages/PD-PABZ-087-3.jpg)
Figure 3 Competitive binding of 2 nM [H3]-morphine against 6-MAM (D), heroin (E) and hydrocodone (F) with 9B1 (20 nM).
Zhang, C. H., Kim, K., Jin, Z., Zheng, F., & Zhan, C. G. (2020). Systematic Structure-Based Virtual Screening Approach to Antibody Selection and Design of a Humanized Antibody against Multiple Addictive Opioids without Affecting Treatment Agents Naloxone and Naltrexone. ACS chemical neuroscience, 12(1), 184-194.
![Figure 4 Competitive binding of 2 nM [H3]-morphine against 6-MAM (G), heroin (H) and hydrocodone (I) with h9B1 (60 nM).](https://img.creativebiolabs.net/productimages/PD-PABZ-087-4.jpg)
Figure 4 Competitive binding of 2 nM [H3]-morphine against 6-MAM (G), heroin (H) and hydrocodone (I) with h9B1 (60 nM).
Zhang, C. H., Kim, K., Jin, Z., Zheng, F., & Zhan, C. G. (2020). Systematic Structure-Based Virtual Screening Approach to Antibody Selection and Design of a Humanized Antibody against Multiple Addictive Opioids without Affecting Treatment Agents Naloxone and Naltrexone. ACS chemical neuroscience, 12(1), 184-194.
Figure 5 (J) Screening of 9B1 and h9B1 against other drugs at 10 μM.
Zhang, C. H., Kim, K., Jin, Z., Zheng, F., & Zhan, C. G. (2020). Systematic Structure-Based Virtual Screening Approach to Antibody Selection and Design of a Humanized Antibody against Multiple Addictive Opioids without Affecting Treatment Agents Naloxone and Naltrexone. ACS chemical neuroscience, 12(1), 184-194.
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- Mouse IgG
- Clone
- 9B1
- Applications
- WB, ELISA
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Morphine
Related Resources
Morphine Addiction
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone 9B1"
See other products for "Morphine"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0230CQ | Mouse Anti-Morphine Recombinant Antibody (clone 10C3) | ELISA | Mouse IgG, λ |
| FAMAB-0231CQ | Mouse Anti-Morphine Recombinant Antibody (clone 11C7) | ELISA | Mouse IgG, λ |
| FAMAB-0232CQ | Mouse Anti-Morphine Recombinant Antibody (clone 12D4) | ELISA | Mouse IgG, λ |
| FAMAB-0233CQ | Mouse Anti-Morphine Recombinant Antibody (clone 3B9) | ELISA | Mouse IgG, λ |
| FAMAB-0234CQ | Mouse Anti-Morphine Recombinant Antibody (clone MOR115) | ELISA | Mouse IgG, λ |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0230CQ-F(E) | Mouse Anti-Morphine Recombinant Antibody (clone 10C3); Fab Fragment | ELISA | Mouse Fab |
| FAMAB-0231CQ-F(E) | Mouse Anti-Morphine Recombinant Antibody (clone 11C7); Fab Fragment | ELISA | Mouse Fab |
| FAMAB-0232CQ-F(E) | Mouse Anti-Morphine Recombinant Antibody (clone 12D4); Fab Fragment | ELISA | Mouse Fab |
| FAMAB-0233CQ-F(E) | Mouse Anti-Morphine Recombinant Antibody (clone 3B9); Fab Fragment | ELISA | Mouse Fab |
| FAMAB-0234CQ-F(E) | Mouse Anti-Morphine Recombinant Antibody (clone MOR115); Fab Fragment | ELISA | Mouse Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0230CQ-S(P) | Mouse Anti-Morphine Recombinant Antibody (clone 10C3); scFv Fragment | ELISA | Mouse scFv |
| FAMAB-0231CQ-S(P) | Mouse Anti-Morphine Recombinant Antibody (clone 11C7); scFv Fragment | ELISA | Mouse scFv |
| FAMAB-0232CQ-S(P) | Mouse Anti-Morphine Recombinant Antibody (clone 12D4); scFv Fragment | ELISA | Mouse scFv |
| FAMAB-0233CQ-S(P) | Mouse Anti-Morphine Recombinant Antibody (clone 3B9); scFv Fragment | ELISA | Mouse scFv |
| FAMAB-0234CQ-S(P) | Mouse Anti-Morphine Recombinant Antibody (clone MOR115); scFv Fragment | ELISA | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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