Anti-Human NPR1 Recombinant Antibody (5064) (CAT#: TAB-571MZ)

This monoclonal antibody is able to bind and stabilize the activated NPRA receptor and enhances the activity of natriuretic peptides.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Published Data
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
FC

Figure 1 Dose Response of Binding of 5064 in Different Formats to NPRA transfected HEK cells.

Figure 1 Dose Response of Binding of 5064 in Different Formats to NPRA transfected HEK cells.

ELISA

Figure 2 Demonstration of Binding of 5064 Fab-dH LX to NPRA-Fc by ELISA.

Figure 2 Demonstration of Binding of 5064 Fab-dH LX to NPRA-Fc by ELISA.

Binding was tested in presence and absence of ligands. Binding to control Fc antigen (neg control antigen) was tested in presence and absence of ANP.

FuncS

Figure 3 Affinity matured Fabs enhance the NPRA mediated cGMP response to both ANP and BNP.

Figure 3 Affinity matured Fabs enhance the NPRA mediated cGMP response to both ANP and BNP.

FuncS

Figure 4 5502, 5504 and 5064 enhance the binding of 125I ANP to HEK NPRA cells as compared to the control antibody 3207.

Figure 4 5502, 5504 and 5064 enhance the binding of 125I ANP to HEK NPRA cells as compared to the control antibody 3207.


Specifications

  • Host Species
  • Human
  • Derivation
  • Phage display library
  • Type
  • Human antibody
  • Specificity
  • Human
  • Clone
  • 5064
  • Applications
  • ELISA, FC, FuncS
  • Related Disease
  • Diseases associated with Natriuretic peptide receptor A

Applications

  • Application Notes
  • This antibody has been reported for use in Enzyme-linked Immunosorbent Assay, Flow Cytotoxicityometry, Functional Assay.

Target

  • Alternative Names
  • ANPa; NPRA; ANPRA; GUC2A; GUCY2A

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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See other products for "Clone 5064"

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Recombinant Antibody

CAT Product Name Application Type
MOB-2414z Mouse Anti-NPR1 Recombinant Antibody (clone 42B9) WB, ELISA, IF, IHC, IP Mouse IgG1, κ

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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