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Anti-NRG1 scFv (10bM3) (TAB-581MZ-S(P))

This antibody specifically recognizes isoforms of the human NRG1 protein, and enables signaling involving these isoforms to be suppressed, such as human NRG1-α protein and NRG1-β1 protein. It is also found to have inhibitory activity against cleavage of the NRG1 protein, inhibitory activity against the phosphorylation of the ErbB3 protein in cancer cells, as well as inhibitory activity against the proliferation of cancer in vivo.      

Specifications
Immunogen
Recombinant human NRG1 protein
Host
Mouse
Specificity
Human
Clone
10bM3
Applications
Enzyme-linked Immunosorbent Assay, Flow Cytometry
Related Disease
Cancer associated with human NRG1 protein
Target
Alternative Names
NRG1; neuregulin 1; GGF; HGL; HRG; NDF; ARIA; GGF2
Entrez Gene ID
3084
UniProt ID
A6MW56

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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