Recombinant Mouse Anti-PfMSP1-19 Antibody (G17.12) (CAT#: PABW-101)
Recombinant Mouse Antibody (G17. 12) is capable of binding to PfMSP1-19, expressed in Chinese Hamster Ovary cells (CHO). G17. 12 antibody recognises a discontinuous epitope comprising 13 residues on the first epidermal growth factor (EGF)-like domain of PfMSP1-19.
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Figure 1 PfMSP119 production in the pPM121 transformed plants as measured by sandwich ELISA.
Two different monoclonal antibodies, G.17.12 and 2F.10 were used in the experiment. (A) Plant extracts crossreacted with monoclonal antibody G.17.12. C, Untransformed plants; 2, 4, 6, 12 are the transformed plants which were assayed for the PfMSP119 production in the experiment. (B) Plant extracts crossreacted with monoclonal antibody 2F.10. C: Untransformed plants; 2, 4, 6, 12 are the transformed plants, which were assayed for the PfMSP119 production in the experiment.
Ghosh, S., Malhotra, P., Lalitha, P. V., Guha-Mukherjee, S., & Chauhan, V. S. (2002). Expression of Plasmodium falciparum C-terminal region of merozoite surface protein (PfMSP119), a potential malaria vaccine candidate, in tobacco. Plant Science, 162(3), 335-343.
Figure 2 Immunoblot detection of PfMSP119 protein in transgenic tobacco plants.
All the plant extracts (transformed and untransformed plants) having 5 mg of total soluble protein. (A) Cross-reactivity of plant derived PfMSP119 protein with polyclonal antibody raised in rabbit against bacterial (E. coli ) PfMSP119 protein. Lane 1 and 4, extracts from plant numbers 4 to 6, respectively. Lane 2 and 5, extract from untransformed plants. Lane 7, bacterial protein (E. coli ). Lane 8, Gibco BRL protein marker. Lane 3 and 6, blank. (B) Cross-reactivity of transgenic plant derived PfMSP119 with monoclonal antibody G17.12. Lane 1, bacterial protein (E. coli ). Lane 2, extract from plant number 6 (containing 5 mg of total soluble protein). Lane 3, untransformed plant extract.
Ghosh, S., Malhotra, P., Lalitha, P. V., Guha-Mukherjee, S., & Chauhan, V. S. (2002). Expression of Plasmodium falciparum C-terminal region of merozoite surface protein (PfMSP119), a potential malaria vaccine candidate, in tobacco. Plant Science, 162(3), 335-343.
Specifications
- Immunogen
- P. falciparum merozoite surface protein 1 precursor
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- IgG
- Specificity
- Tested positive against native PfMSP1-19
- Species Reactivity
- P. falciparum
- Clone
- G17.12
- Applications
- ELISA, WB, BL
Product Property
- Purity
- >95% by SDS-PAGE and HPLC analysis
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Applications
- Application Notes
- The MSP1 antibody has been reported in applications of ELISA, WB.
Target
- Alternative Names
- merozoite surface antigen 1; MSA1; MSP-1; Pf190; PMMSA
- Gene ID
- 813575
- UniProt ID
- Q8I0U8
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBW-101 | Recombinant Mouse Anti-PfMSP1-19 Antibody Fab Fragment (G17.12) | ELISA, WB, BL | IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBW-101 | Recombinant Mouse Anti-PfMSP1-19 Antibody scFv Fragment (G17.12) | ELISA, WB, BL | scFv |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-014CT | Recombinant Mouse Anti-Plasmodium falciparum MSP1 Antibody | ELISA, WB |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0423-XY19 | Human Anti-MSP1 Recombinant Antibody (clone D3) | ELISA, IF | Human IgG |
| VS-0423-XY20 | Human Anti-MSP1 Recombinant Antibody (clone C1) | ELISA, IF | Human IgG |
| VS-0423-XY21 | Human Anti-MSP1 Recombinant Antibody (clone D4) | ELISA, IF | Human IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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