Mouse Anti-RAMP1 Recombinant Antibody (clone JF2) (CAT#: NS-068CN)

The anti-RAMP1 antibody is capable of binding to RAMP1, RAMP2 or RAMP3. The antibody can be used in the treatment of tumors.


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FuncS

Figure 1 The effect of the monoclonal antibodies on the growth of SW-13 cells in vitro.

Figure 1 The effect of the monoclonal antibodies on the growth of SW-13 cells in vitro.

Monoclonal anti-RAMP-3 antibodies were tested for their ability to induce inhibition of proliferation of SW-13 (adrenocarcinoma cells). The concentration of 1 :50 equates to about 5ng per well final concentration.

FuncS

Figure 2 A MTT assay assessing the rate of proliferation in the U-87 glioblastoma cell line in the presence of antibody JF2 at varying concentrations (after 8 days of culture).

Figure 2 A MTT assay assessing the rate of proliferation in the U-87 glioblastoma cell line in the presence of antibody JF2 at varying concentrations (after 8 days of culture).

FuncS

Figure 3 A MTT assay assessing the rate of proliferation in the MDA-MB-436-GFP breast cancer cell line in the presence of antibody JF2 at varying concentrations (after 8 days of culture).

Figure 3 A MTT assay assessing the rate of proliferation in the MDA-MB-436-GFP breast cancer cell line in the presence of antibody JF2 at varying concentrations (after 8 days of culture).

FuncS

Figure 4 A MTT assay assessing the rate of proliferation in the PC-3 prostate cancer cell line in the presence of antibody JF2 at a concentration of 10Mg (after 8 days of culture).

Figure 4 A MTT assay assessing the rate of proliferation in the PC-3 prostate cancer cell line in the presence of antibody JF2 at a concentration of 10Mg (after 8 days of culture).

Apop

Figure 5 An apoptosis assay assessing the levels of caspase-3 a marker in U-87 glioblastoma cancer cell line in the presence of antibody JB3 and JF2.

Figure 5 An apoptosis assay assessing the levels of caspase-3 a marker in U-87 glioblastoma cancer cell line in the presence of antibody JB3 and JF2.

Apop

Figure 6 An apoptosis assay assessing the levels of caspase-3 a marker in a MDA-MB-436-GFP breast cancer cell line in the presence of antibody JB3 and JF2.

Figure 6 An apoptosis assay assessing the levels of caspase-3 a marker in a MDA-MB-436-GFP breast cancer cell line in the presence of antibody JB3 and JF2.

FuncS

Figure 7 The tumour volume of MDA-MB-436-GFP injected into the right flank of CD1 nude mice, treated with JF2 antibody and controls over a period of 6 weeks.

Figure 7 The tumour volume of MDA-MB-436-GFP injected into the right flank of CD1 nude mice, treated with JF2 antibody and controls over a period of 6 weeks.


Specifications

  • Immunogen
  • A peptide corresponding to an extracellular domain of RAMP-3
  • Host Species
  • Mouse
  • Type
  • Mouse IgG1
  • Specificity
  • Human RAMP1
  • Species Reactivity
  • Human
  • Clone
  • JF2
  • Applications
  • ELISA, WB, Apop, FuncS
  • Related Disease
  • Tumor

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • This antibody has been tested for use in Apoptosis, Functional Assay.

Target

  • Alternative Names
  • Receptor activity modifying protein 1

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone JF2"

See other products for "RAMP1"

Recombinant Antibody

CAT Product Name Application Type
MOB-2606z Mouse Anti-RAMP1 Recombinant Antibody (clone 32A11) WB, ELISA, IP Mouse IgG2b, κ

Rabbit Monoclonal Antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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