Anti-Human ROBO1 Recombinant Antibody (A7241A) (CAT#: TAB-0281CL)
The anti-ROBO1 antibody (A7241A) specifically binds to roundabout homolog 1, which has be identified as a molecule regulating the midline crossing of anxon and has been reported to work as a receptor for the Slit protein in subsequent studies. The specific antibody can be used for the diagnosis and treatment studies of cancer and a method for monitoring progression of hepatitis.
Specific Inquiry
IB
Figure 1 Characterization of recombinant ROBO1 and endogenous ROBO1 with anti-ROBO1 mAbs.
Immunoblotting analysis of recombinant ROBO1with themAb A7241A.
Ito, H., Funahashi, S. I., Yamauchi, N., Shibahara, J., Midorikawa, Y., Kawai, S., ... & Iwanari, H. (2006). Identification of ROBO1 as a novel hepatocellular carcinoma antigen and a potential therapeutic and diagnostic target. Clinical Cancer Research, 12(11), 3257-3264.
IHC
Figure 2 Immunohistochemical analysis of ROBO1.
A, H&E staining of poorly differentiated hepatocellular carcinoma. B, poorly differentiated hepatocellular carcinomaimmunostained with the mAb A7241A (serial section adjacent to the H&E-stained specimen A). Magnification, 40. Strong staining was observed inhepatocellularcarcinoma but notin noncancerous areas. C, well-diffe rentia ted he patocellular c arcinoma. Magnifi cation, 200. D, moderately differentiated hepatocellular carcinoma.Magnific ation, 200. E, poorly differentiated hepatocellular carcinoma. Magnification, 200.The epithelium of poorly differentiated hepatocellular carcinoma was labeledstrongly with the mAb A7241A.
Ito, H., Funahashi, S. I., Yamauchi, N., Shibahara, J., Midorikawa, Y., Kawai, S., ... & Iwanari, H. (2006). Identification of ROBO1 as a novel hepatocellular carcinoma antigen and a potential therapeutic and diagnostic target. Clinical Cancer Research, 12(11), 3257-3264.
Specifications
- Host Species
- Mouse
- Specificity
- Human
- Clone
- A7241A
- Applications
- IB, IHC
- Related Disease
- Hepatitis
Applications
- Application Notes
- This antibody has been reported for use in Immunoblot and Immunofluorescence and Immunohistochemistry.
Target
- Alternative Names
- ROBO1; roundabout; axon guidance receptor; homolog 1 (Drosophila); SAX3; DUTT1; roundabout homolog 1; deleted in U twenty twenty
- Gene ID
- 6091
- UniProt ID
- Q9Y6N7
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "Clone A7241A"
See other products for "ROBO1"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-346 | Mouse Anti-ROBO1 Recombinant Antibody (PABL-346) | WB, ELISA, FuncS | Mouse IgG2a kappa |
| MOB-1275MZ | Recombinant Mouse Anti-Human ROBO1 Antibody (clone 2G6) | WB | Mouse antibody |
| MRO-2166-CN | Rabbit Anti-ROBO1 Polyclonal Antibody (MRO-2166-CN) | IF, IHC | Rabbit IgG |
| PABJ-0064 | Mouse Anti-ROBO1 Recombinant Antibody (PABJ-0064) | ELISA, FuncS | Mouse IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-346 | Mouse Anti-ROBO1 Recombinant Antibody; scFv Fragment (PSBL-346) | WB, ELISA, FuncS | Mouse scFv |
| PABJ-0064-S(P) | Mouse Anti-ROBO1 Recombinant Antibody; scFv Fragment (PABJ-0064-S(P)) | ELISA, FuncS | Mouse scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-346 | Mouse Anti-ROBO1 Recombinant Antibody; Fab Fragment (PFBL-346) | WB, ELISA, FuncS | Mouse Fab |
| PABJ-0064-F(E) | Mouse Anti-ROBO1 Recombinant Antibody; Fab Fragment (PABJ-0064-F(E)) | ELISA, FuncS | Mouse Fab |
Mouse Antibody
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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