Products

Afelimomab (TAB-718)

Recombinant mouse monoclonal antibody F(ab')2 fragment expressed in CHO binding to human TNFα. Afelimomab is an anti-TNFα monoclonal antibody. Administration of afelimomab reduces the concentration of interleukin-6 in patients with sepsis, but reduces mortality only marginally.      

Specifications
Immunogen
The details of the immunogen for this antibody are not available.
Host
Mouse
Derivation
Mouse
Type
F(ab')2 - G3 - kappa
Species Reactivity
Human
Applications
Suitable for use in Neut, ELISA, IF, IP, FuncS, FC, ICC and most other immunological methods.
CAS NO.
156227-98-4
Generic Name
Afelimomab
ATC Code
L04AB03
Related Disease
Sepsis toxic shock
Target
Alternative Names
Afelimomab; 156227-98-4; MAK 195F; LU54107; MAK 195F; TNF; tumor necrosis factor; TNFA, tumor necrosis factor (TNF superfamily, member 2)
Entrez Gene ID
7124
UniProt ID
P01375

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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