Products

Cetuximab (TP-079CL)

Cetuximab is an epidermal growth factor receptor binding FAB. Cetuximab is composed of the Fv (variable; antigen-binding) regions of the 225 murine EGFr monoclonal antibody specific for the N-terminal portion of human EGFr with human IgG1 heavy and kappa light chain constant (framework) regions. Cetuximab is marketed under the brand Erbitux® by Eli Lilly and Company. In the United States, a regimen of cetuximab costs approximately $30,790 for an eight-week course.      

Specifications
Classify
Protein therapeutics that interfere with a molecule or organism: Cancer
Therapeutic
Cetuximab
Trade Name
Erbitux
Function
Humanized mAb that binds eGFr
Examples of Clinical Use
Colorectal cancer, head and neck cancer
References
Synonyms
Cetuximab, Cétuximab, Cetuximab, Cetuximabum, Immunoglobulin G 1 (human-mouse monoclonal C 225 gamma 1 - chain anti-human epidermal growt factor receptor), disulfide wit human-mouse monoclonal C 225 kappa - chain, dimer
Genbank
J00228

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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