Recombinant monoclonal antibody to CD274. Durvalumab is a human monoclonal antibody that can be potentially used in the treatment of Cancers, non-small cell lung (NSCLC), Solid tumors, bladder, urothelial.
Figure 1 Monalizumab and Durvalumab Unleash NK and CD8 + T Cell Function In Vitro.
NK cells were co-cultured with K562 or K562 cells expressing HLA-E in the presence or absence of monalizumab. The frequencies of CD107-positive NK cells are shown. Box and whiskers plot, with the means indicated by crosses. N = 8. The whiskers are drawn down to the 25th percentile minus 1.5 times IQR (interquartile range) and up to the 75th percentile plus 1.5 times IQR. Friedman analysis followed by Dunn's multiple comparisons test. **p = 0.006; ***p = 0.0001.
André, P., Denis, C., Soulas, C., Bourbon-Caillet, C., Lopez, J., Arnoux, T.,... & Rossi, B. (2018). Anti-NKG2A mAb is a checkpoint inhibitor that promotes anti-tumor immunity by unleashing both T and NK cells. Cell, 175(7), 1731-1743.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Afuco™ Anti-CD274 ADCC Recombinant Antibody (Durvalumab), ADCC EnhancedThis product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to CD274. Durvalumab is a human monoclonal antibody that can be potentially used in the treatment of Cancers, non-small cell lung (NSCLC), Solid tumors, bladder, urothelial.
CAT | Product Name | Application | Type |
---|---|---|---|
NAB-305-sdAb | Recombinant Anti-Mouse Cd274 VHH Single Domain Antibody | IHC, IP, FC, Neut, FUNC | Llama VHH |
HPAB-N0408-YC-VHH | Recombinant Humanized Anti-CD274 Single Domain Antibody (PDL1-56dAb) | ELISA, FC, BL | Human VHH |
HPAB-N0307-YC-VHH | Recombinant Humanized Anti-CD274 Single Domain Antibody (NOV013YC) | ELISA, FC, BL | Humanized VHH |
NBD-0065-YJ-VHH | Camelid Anti-CD274 Recombinant Single Domain Antibody (CBP112D) | ELISA | Camelid VHH |
NBD-0066-YJ-VHH | Camelid Anti-CD274 Recombinant Single Domain Antibody (KN035) | ELISA, Inihb | Camelid VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0262CL | Mouse Anti-CD274 Recombinant Antibody (TAB-0262CL) | ELISA, WB, SPR, ADCC, CDC, FuncS | Mouse IgG |
TAB-0262CL-S(P) | Mouse Anti-CD274 Recombinant Antibody; scFv Fragment (TAB-0262CL-S(P)) | ELISA, WB, SPR, FuncS | Mouse scFv |
TAB-1009CL-F(E) | Mouse Anti-CD274 Recombinant Antibody; Fab Fragment (TAB-1009CL-F(E)) | WB, IHC | Mouse Fab |
TAB-1010CL-F(E) | Anti-Human CD274 Recombinant Antibody Fab Fragment | FC | |
TAB-1011CL-F(E) | Mouse Anti-CD274 Recombinant Antibody; Fab Fragment (TAB-1011CL-F(E)) | ELISA | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0263CL | Human Anti-CD274 Recombinant Antibody (TAB-0263CL) | ELISA, WB, SPR, FuncS | Humanized IgG |
TAB-0264CL | Human Anti-CD274 Recombinant Antibody (TAB-0264CL) | ELISA, WB, SPR, ADCC, CDC, FuncS, Inhib | Humanized IgG |
TAB-0996CL | Human Anti-CD274 Recombinant Antibody (TAB-0996CL) | ELISA, FC | Human IgG1, κ |
TAB-0996CL-S(P) | Human Anti-CD274 Recombinant Antibody; scFv Fragment (TAB-0996CL-S(P)) | ELISA, FC | Human scFv |
TAB-0996CL-F(E) | Human Anti-CD274 Recombinant Antibody; Fab Fragment (TAB-0996CL-F(E)) | ELISA, FC | Humanized Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0995CL | Human Anti-CD274 Recombinant Antibody (TAB-0995CL) | ELISA, FC | Chimeric (Mouse/Human) IgG1, κ |
TAB-0995CL-S(P) | Human Anti-CD274 Recombinant Antibody; scFv Fragment (TAB-0995CL-S(P)) | ELISA, FC | Human scFv |
TAB-0995CL-F(E) | Human Anti-CD274 Recombinant Antibody; Fab Fragment (TAB-0995CL-F(E)) | ELISA, FC | Chimeric (Mouse/Human) Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-1000CL-S(P) | Human Anti-CD274 Recombinant Antibody; scFv Fragment (TAB-1000CL-S(P)) | ELISA | Human scFv |
TAB-1001CL-S(P) | Human Anti-CD274 Recombinant Antibody; scFv Fragment (TAB-1001CL-S(P)) | FC | Human scFv |
TAB-0998CL-F(E) | Anti-Human CD274 Recombinant Antibody Fab Fragment (BII61-62) | ELISA | Human antibody |
TAB-0999CL-F(E) | Anti-Human CD274 Recombinant Antibody Fab Fragment (B50-6) | ELISA | Human antibody |
TAB-1000CL-F(E) | Human Anti-CD274 Recombinant Antibody; Fab Fragment (TAB-1000CL-F(E)) | ELISA | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-324CQ | Mouse Anti-CD274 Recombinant Antibody (clone 29E.2A3.C6) | IHC-P, FC, Neut, ICC | Mouse IgG2b, κ |
NEUT-325CQ | Human Anti-CD274 Recombinant Antibody (clone CBLS-206) | Neut | Human IgG1, κ |
NEUT-326CQ | Human Anti-CD274 Recombinant Antibody (clone CBLS-207) | ELISA, Neut | Human IgG1, κ |
NEUT-327CQ | Mouse Anti-CD274 Recombinant Antibody (clone MIH1) | FC, FuncS, Neut, IHC, IF | Mouse IgG1, κ |
NEUT-330CQ | Rat Anti-CD274 Recombinant Antibody (clone MIH5) | FC, FuncS, Neut, IHC-Fr, WB | Rat IgG2a, λ |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-328CQ | Rat Anti-CD274 Recombinant Antibody (VMC171) | Block, FC | Rat IgG2 |
NEUT-329CQ | Rat Anti-CD274 Recombinant Antibody (clone 10F.9G2) | FC, IF, Block | Rat IgG2b, κ |
NEUT-331CQ | Mouse Anti-CD274 Recombinant Antibody (clone alphaPD-L1) | ELISA, Block | Mouse IgG1, λ |
NEUT-332CQ | Rabbit Anti-CD274 Recombinant Antibody (clone CBL1009) | Block | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-0548 | Hi-Affi™ Rabbit Anti-CD274 Recombinant Antibody (clone DS548AB) | ELISA | Rabbit IgG |
MOR-4049 | Hi-Affi™ Rabbit Anti-CD274 Recombinant Antibody (clone SI116DS) | ELISA | Rabbit IgG |
MOR-4050 | Hi-Affi™ Rabbit Anti-CD274 Recombinant Antibody (clone SI117DS) | ICC, IF, FC | Rabbit IgG |
MOR-4051 | Hi-Affi™ Rabbit Anti-CD274 Recombinant Antibody (clone SI118DS) | FC | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0193-YC-F(E) | Human Anti-CD274 Recombinant Antibody; Fab Fragment (HPAB-0193-YC-F(E)) | ELISA | Humanized Fab |
HPAB-0194-YC-F(E) | Mouse Anti-CD274 Recombinant Antibody; Fab Fragment (HPAB-0194-YC-F(E)) | ELISA | Mouse Fab |
HPAB-0195-YC-F(E) | Human Anti-CD274 Recombinant Antibody; Fab Fragment (HPAB-0195-YC-F(E)) | SPR | Humanized Fab |
HPAB-0196-YC-F(E) | Human Anti-CD274 Recombinant Antibody; Fab Fragment (HPAB-0196-YC-F(E)) | FC | Human Fab |
HPAB-0197-YC-F(E) | Rabbit Anti-CD274 Recombinant Antibody; Fab Fragment (HPAB-0197-YC-F(E)) | ELISA, FC | Rabbit Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-1440LY | Human Anti-CD274 Recombinant Antibody (clone 28-8) | IHC | Chimeric (Rabbit/Human) IgG1 |
HPAB-0528LY | Human Anti-CD274 Recombinant Antibody (clone 047HAb-1) | ELISA | Human IgG1 |
HPAB-0529LY | Human Anti-CD274 Recombinant Antibody (clone 047HAb-2) | ELISA | Human IgG1 |
HPAB-0530LY | Human Anti-CD274 Recombinant Antibody (clone 047HAb-3) | ELISA | Human IgG1 |
HPAB-0531LY | Human Anti-CD274 Recombinant Antibody (clone 047HAb-4) | ELISA | Human IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-417CQ | Afuco™ Anti-CD274 ADCC Recombinant Antibody (Durvalumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, Inhib | ADCC enhanced antibody |
AFC-TAB-418CQ | Afuco™ Anti-CD274 ADCC Recombinant Antibody (Atezolizumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, BL | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-1668-FY-F(E) | Human Anti-CD274 Recombinant Antibody; Fab Fragment (HPAB-1668-FY-F(E)) | FC | Human Fab |
HPAB-0502YY-S(P) | Human Anti-CD274 Recombinant Antibody (clone Q1-43); scFv Fragment | ELISA | Human scFv |
HPAB-0505YY-S(P) | Human Anti-CD274 Recombinant Antibody (clone Q2-33); scFv Fragment | ELISA | Human scFv |
HPAB-0506YY-S(P) | Human Anti-CD274 Recombinant Antibody (clone Q2-20); scFv Fragment | ELISA | Human scFv |
HPAB-0509YY-S(P) | Human Anti-CD274 Recombinant Antibody; scFv Fragment (HPAB-0509YY-S(P)) | ELISA, FC | Human scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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