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  • PE-A*02:03/Human LMNB1 (RLAVYIDKV) MHC Tetramer

PE-A*02:03/Human LMNB1 (RLAVYIDKV) MHC Tetramer (CAT#: MHC-LC3731)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human LMNB1 of peptide RLAVYIDKV covering 42-50 and A*02:03 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.


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  • Gene Expression
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Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line MCF7
Figure 1 IF staining of human cell line MCF7
(Immunofluorescent staining of human cell line MCF7 shows localization to nuclear membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50524/if_selected.jpg
Figure 2 IF staining of human cell line U-251 MG
Figure 2 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nuclear membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5269/950_C1_1_selected.jpg
Figure 3 IF staining of human cell line U-2 OS
Figure 3 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nuclear membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/79757/1894_G3_4_selected.jpg
Figure 4 IHC staining of human colon
Figure 4 IHC staining of human colon
(Immunohistochemical staining of human colon shows nuclear membrane positivity in glandular and stroma cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50524/ihc_selected.jpg
Figure 5 IHC staining of human stomach
Figure 5 IHC staining of human stomach
(Immunohistochemical staining of human stomach shows strong nuclear membranous positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5269/155655_A_3_1_selected.jpg
Figure 6 IHC staining of human esophagus
Figure 6 IHC staining of human esophagus
(Immunohistochemical staining of human esophagus shows strong nuclear positivity in squamous epithelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/79954/171056_B_6_1_selected.jpg
Normal Tissue
Figure 7 Cerebral cortex
Figure 7 Cerebral cortex
(Glial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Neuronal cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50524/140330_B_8_5.jpg
Figure 8 Kidney
Figure 8 Kidney
(Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Hepatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50524/140330_A_7_4.jpg
Figure 9 Testis
Figure 9 Testis
(Cells in seminiferous ducts
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50524/140330_A_5_6.jpg
Figure 10 Lymph node
Figure 10 Lymph node
(Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50524/140330_A_8_8.jpg
RNA Expression
Figure 11 RNA cell line category: Low cell line specificity
Figure 11 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000113368-LMNB1

Specifications

  • Allele
  • A*02:03
  • Class
  • Class I
  • Antigen
  • LMNB1
  • Antigen Species
  • Human
  • Peptide
  • RLAVYIDKV
  • Range
  • 42-50
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • This gene encodes one of the two B-type lamin proteins and is a component of the nuclear lamina. A duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
  • Alternative Names
  • LMNB1; Lamin-B1; LMN; ADLD; LMN2; LMNB

Downloads

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See other products for "LMNB1"

Recombinant Antibody

CAT Product Name Application Type
MOB-1818z Mouse Anti-LMNB1 Recombinant Antibody (clone 19G6) ELISA, IHC, WB Mouse IgG2a, κ
MRO-2006-CN Rabbit Anti-LMNB1 Polyclonal Antibody (MRO-2006-CN) WB Rabbit IgG
ZG-0264C Mouse Anti-LMNB1 Recombinant Antibody (ZG-0264C) WB Mouse IgG
VS3-FY834 Recombinant Mouse Anti-LMNB1 Antibody (VS3-FY834) WB, IP Mouse IgG
VS3-FY852 Recombinant Rabbit Anti-LMNB1 Antibody (clone R05-8D6) WB, IHC-P, IP Rabbit IgG

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-2068 Hi-Affi™ Recombinant Rabbit Anti-LMNB1 Monoclonal Antibody (DS2068AB) WB, IHC, IP IgG
MOR-0075-FY Rabbit Anti-LMNB1 Recombinant Antibody (clone AFY0046) ICC, IHC-P, WB Rabbit IgG

MHC Tetramer for Cancer

CAT Product Name Application Type
MHC-LC3725 PE-A*02:02/Human LMNB1 (ELRELNDRL) MHC Tetramer FCM
MHC-LC3726 PE-A*02:01/Human LMNB1 (ELRELNDRL) MHC Tetramer FCM
MHC-LC3727 PE-A*68:02/Human LMNB1 (ELRELNDRL) MHC Tetramer FCM
MHC-LC3728 PE-A*02:01/Human LMNB1 (RLAVYIDKV) MHC Tetramer FCM
MHC-LC3729 PE-A*68:02/Human LMNB1 (RLAVYIDKV) MHC Tetramer FCM

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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