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PE-A*11:01/Human RPS3 (RTQNVLGEK) MHC Tetramer (CAT#: MHC-LC2370)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human RPS3 of peptide RTQNVLGEK covering 54-62 and A*11:01 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.


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Specific Inquiry
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  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Figure 1 IF staining of human cell line MCF7
Figure 1 IF staining of human cell line MCF7
(Immunofluorescent staining of human cell line MCF7 shows localization to cytosol & endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/63339/1230_E7_1_selected.jpg
Normal Tissue
Figure 2 IHC staining of human skin
Figure 2 IHC staining of human skin
(Immunohistochemical staining of human skin shows strong cytoplasmic positivity in epidermal cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/63339/ihc_selected.jpg
Figure 3 Cerebral cortex
Figure 3 Cerebral cortex
(Glial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/63339/142624_B_8_5.jpg
Figure 4 Colon
Figure 4 Colon
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/63339/142624_A_9_3.jpg
Figure 5 Liver
Figure 5 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/63339/142624_A_9_4.jpg
Figure 6 Kidney
Figure 6 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/63339/142624_A_8_5.jpg
Figure 7 Testis
Figure 7 Testis
(Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/63339/142624_A_6_6.jpg
Figure 8 Lymph node
Figure 8 Lymph node
(Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/63339/142624_A_8_8.jpg
RNA Expression
Figure 9 RNA cell line category: Low cell line specificity
Figure 9 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000149273-RPS3

Specifications

  • Allele
  • A*11:01
  • Class
  • Class I
  • Antigen
  • RPS3
  • Antigen Species
  • Human
  • Peptide
  • RTQNVLGEK
  • Range
  • 54-62
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit, where it forms part of the domain where translation is initiated. The protein belongs to the S3P family of ribosomal proteins. Studies of the mouse and rat proteins have demonstrated that the protein has an extraribosomal role as an endonuclease involved in the repair of UV-induced DNA damage. The protein appears to be located in both the cytoplasm and nucleus but not in the nucleolus. Higher levels of expression of this gene in colon adenocarcinomas and adenomatous polyps compared to adjacent normal colonic mucosa have been observed. This gene is co-transcribed with the small nucleolar RNA genes U15A and U15B, which are located in its first and fifth introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
  • Alternative Names
  • RPS3; 40S ribosomal protein S3; S3

Downloads

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See other products for "RPS3"

Recombinant Antibody

CAT Product Name Application Type
MOB-2414CT Recombinant Mouse anti-Human RPS3 Monoclonal antibody (FQS4883) WB, ELISA
MRO-1348-CN Recombinant Rabbit Anti-RPS3 Monoclonal Antibody (CBACN-490) WB, IF, IHC Rabbit IgG
VS3-CJ799 Rabbit Anti-RPS3 Recombinant Antibody (VS3-CJ799) WB, ICC, IHC Rabbit IgG

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-3119 Hi-Affi™ Recombinant Rabbit Anti-RPS3 Monoclonal Antibody (DS3119AB) WB, IHC, ICC IgG

MHC Tetramer for Cancer

CAT Product Name Application Type
MHC-LC2369 PE-A*03:01/Human RPS3 (RTQNVLGEK) MHC Tetramer FCM

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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