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APC-B*07:02/Human ELAVL1 (NPNQNKNVAL) MHC Tetramer (CAT#: MHC-LC2089)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human ELAVL1 of peptide NPNQNKNVAL covering 186-195 and B*07:02 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.


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Subcellular Location
Figure 1 IF staining of human cell line A-431
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5256/if_selected.jpg
Normal Tissue
Figure 2 IHC staining of human parathyroid gland
Figure 2 IHC staining of human parathyroid gland
(Immunohistochemical staining of human parathyroid gland shows strong nuclear positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5256/ihc_selected.jpg
Figure 3 Cerebral cortex
Figure 3 Cerebral cortex
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Glial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: nuclear Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5256/13674_B_7_5.jpg
Figure 4 Colon
Figure 4 Colon
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5256/13674_A_7_3.jpg
Figure 5 Kidney
Figure 5 Kidney
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: nuclear Cells in tubules Staining: Low Intensity: Weak Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5256/13674_A_8_5.jpg
Figure 6 Testis
Figure 6 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: nuclear Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5256/13674_A_4_6.jpg
RNA Expression
Figure 7 RNA cell line category: Low cell line specificity
Figure 7 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000066044-ELAVL1

Specifications

  • Allele
  • B*07:02
  • Class
  • Class I
  • Antigen
  • ELAVL1
  • Antigen Species
  • Human
  • Peptide
  • NPNQNKNVAL
  • Range
  • 186-195
  • Conjugate
  • APC
  • Application
  • FCM

Target

  • Antigen Introduction
  • The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. [provided by RefSeq, Sep 2012]
  • Alternative Names
  • ELAVL1; ELAV-like protein 1; HUR; Hua; MelG; ELAV1

Downloads

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See other products for "ELAVL1"

Recombinant Antibody

CAT Product Name Application Type
MOB-1825MZ Recombinant Mouse Anti-Human ELAVL1 Antibody WB Mouse antibody
MRO-0803-CN Rabbit Anti-ELAVL1 Recombinant Antibody (clone JM96-33) WB, IHC, IP, FC Rabbit IgG
VS3-WK995 Mouse Anti-ELAVL1 Recombinant Antibody (VS3-WK995) WB, ICC Mouse IgG

MHC Tetramer for Cancer

CAT Product Name Application Type
MHC-LC2088 PE-B*07:02/Human ELAVL1 (NPNQNKNVAL) MHC Tetramer FCM

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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