Popular Searches: Recombinant Antibody MHC Tetramer T cell Receptor Scaffold Protein
  • Home
  • PTBP1
  • APC-B*07:02/Human PTBP1 (SPNQARAQAAL) MHC Tetramer

APC-B*07:02/Human PTBP1 (SPNQARAQAAL) MHC Tetramer (CAT#: MHC-LC2087)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human PTBP1 of peptide SPNQARAQAAL covering 141-151 and B*07:02 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.


See more MHC Tetramer products for PTBP1
Specific Inquiry
  • Size:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-2 OS
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13507/if_selected.jpg
Figure 2 IHC staining of human small intestine
Figure 2 IHC staining of human small intestine
(Immunohistochemical staining of human small intestine shows strong nuclear positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13507/ihc_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Figure 3 Cerebral cortex
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear
Glial cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13507/30256_B_7_5.jpg
Figure 4 Colon
Figure 4 Colon
(Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13507/30256_A_7_3.jpg
Figure 5 Kidney
Figure 5 Kidney
(Cells in glomeruli
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
Cells in tubules
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13507/30256_A_7_5.jpg
Figure 6 Testis
Figure 6 Testis
(Peritubular cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Preleptotene spermatocytes
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13507/30256_A_6_6.jpg
Figure 7 Lymph node
Figure 7 Lymph node
(Germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13507/30256_A_9_8.jpg
RNA Expression
Figure 8 RNA cell line category: Low cell line specificity
Figure 8 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000011304-PTBP1/subcellular

Specifications

  • Allele
  • B*07:02
  • Class
  • Class I
  • Antigen
  • PTBP1
  • Antigen Species
  • Human
  • Peptide
  • SPNQARAQAAL
  • Range
  • 141-151
  • Conjugate
  • APC
  • Application
  • FCM

Target

  • Antigen Introduction
  • This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has four repeats of quasi-RNA recognition motif (RRM) domains that bind RNAs. This protein binds to the intronic polypyrimidine tracts that requires pre-mRNA splicing and acts via the protein degradation ubiquitin-proteasome pathway. It may also promote the binding of U2 snRNP to pre-mRNAs. This protein is localized in the nucleoplasm and it is also detected in the perinucleolar structure. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
  • Alternative Names
  • PTBP1; Polypyrimidine tract-binding protein 1; PTB; PTB2; PTB3; PTB4; pPTB; HNRPI; PTB-1; PTB-T; HNRNPI; HNRNP-I

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "PTBP1"

Recombinant Antibody

CAT Product Name Application Type
MOB-1658CT Recombinant Mouse anti-Human PTBP1 Monoclonal antibody (EML2203) IHC-P, WB
MRO-1290-CN Recombinant Mouse Anti-PTBP1 Monoclonal Antibody (9A1) WB, IHC, IF, FC Mouse IgG2a
MRO-1291-CN Recombinant Mouse Anti-PTBP1 Monoclonal Antibody (5C1) WB, IHC Mouse IgG1
MRO-1292-CN Recombinant Rabbit Anti-PTBP1 Monoclonal Antibody (JU41-20) WB, IHC Rabbit IgG
MRO-2143-CN Rabbit Anti-PTBP1 Polyclonal Antibody (MRO-2143-CN) WB, IF, IHC Rabbit IgG

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-2911 Hi-Affi™ Recombinant Rabbit Anti-PTBP1 Monoclonal Antibody (DS2911AB) WB, IHC, ICC IgG

MHC Tetramer for Cancer

CAT Product Name Application Type
MHC-LC2086 PE-B*07:02/Human PTBP1 (SPNQARAQAAL) MHC Tetramer FCM

Customer Reviews and Q&As

Submit a review or a question
There are currently no Customer reviews or questions for MHC-LC2087. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.

For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

© 2024 Creative Biolabs.
  • 0
  • 0
Cart
    Inquiry

    Go to compare