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  • A*02:01/Human Fibromodulin (YLLDLSTNHL) MHC Pentamer

A*02:01/Human Fibromodulin (YLLDLSTNHL) MHC Pentamer (CAT#: MHC-YF435)

MHC pentamers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a MHC pentamer of peptide/MHC complex composed Fibromodulin-derived peptide of YLLDLSTNHL sequence covering 7-15 and A*02:01 molecule. The peptide/MHC pentamer provided here is unlabelled or fluorescent labelled, such as Biotin, R-PE, APC. All products are available in 50, 150 and 500 tests.


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RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (ASC diff, CACO-2, HHSteC, HSkMC, OE19)
Figure 1 RNA cell line category: Cell line enhanced (ASC diff, CACO-2, HHSteC, HSkMC, OE19)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000122176-FMOD

Specifications

  • Allele
  • A*02:01
  • Class
  • Class I
  • MHC Species
  • Human
  • Antigen
  • Fibromodulin
  • Antigen Species
  • Human
  • Peptide
  • YLLDLSTNHL
  • Range
  • 7-15
  • Conjugate
  • Unlabeled, Biotin, R-PE, APC
  • Application
  • FCM

Target

  • Antigen Introduction
  • Fibromodulin belongs to the family of small interstitial proteoglycans. The encoded protein possesses a central region containing leucine-rich repeats with 4 keratan sulfate chains, flanked by terminal domains containing disulphide bonds. Owing to the interaction with type I and type II collagen fibrils and in vitro inhibition of fibrillogenesis, the encoded protein may play a role in the assembly of extracellular matrix. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Sequence variations in this gene may be associated with the pathogenesis of high myopia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
  • Alternative Names
  • Fibromodulin; Keratan Sulfate Proteoglycan Fibromodulin; Collagen-Binding 59 KDa Protein; KSPG Fibromodulin; SLRR2E; FM; Fibromodulin Proteoglycan;

Related Resources

  • Related Signaling Pathways

Downloads

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MHC Tetramer for Cancer

CAT Product Name Application Type
MHC-YF434 A*02:01/Human Fibromodulin (LLLAGLFSL) MHC Pentamer FCM
MHC-YF436 A*02:01/Human Fibromodulin (YLQHNEIQEV) MHC Pentamer FCM
MHC-YF437 A*02:01/Human Fibromodulin (YMEHNNVYTV) MHC Pentamer FCM

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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