A*02:01/Human MAGEA1 (KVLEYVIKV) MHC Pentamer (CAT#: MHC-YF529)
MHC pentamers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a MHC pentamer of peptide/MHC complex composed MAGEA1-derived peptide of KVLEYVIKV sequence covering 278-286 and A*02:01 molecule. The peptide/MHC pentamer provided here is unlabelled or fluorescent labelled, such as Biotin, R-PE, APC. All products are available in 50, 150 and 500 tests.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2620/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2620/if_selected.jpg
Figure 2 Cerebral cortex
(Neuronal cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2620/6443_B_8_5.jpg
(Neuronal cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2620/6443_B_8_5.jpg
Figure 3 Kidney
(Cells in glomeruli Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2620/6443_A_7_5.jpg
(Cells in glomeruli Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2620/6443_A_7_5.jpg
Figure 4 High expression in testis.
(Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2620/6443_A_6_6.jpg
(Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2620/6443_A_6_6.jpg
Figure 5 RNA cell line category: Cell line enhanced (HEL, HMC-1, RPMI-8226, U-2 OS, U-266/70, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000198681-MAGEA1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000198681-MAGEA1
Specifications
- Allele
- A*02:01
- Class
- Class I
- Antigen
- MAGEA1
- Antigen Species
- Human
- Peptide
- KVLEYVIKV
- Range
- 278-286
- Conjugate
- Unlabeled, Biotin, R-PE, APC
- Application
- FCM
Target
- Antigen Introduction
- This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. [provided by RefSeq, Jul 2008]
- Alternative Names
- MAGE Family Member A1; Melanoma Antigen Family A, 1 (Directs Expression Of Antigen MZ2-E); Cancer/Testis Antigen Family 1, Member 1; Melanoma-Associated Antigen MZ2-E; Melanoma-Associated Antigen 1; Melanoma Antigen Family A 1; Melanoma Antigen Family A1; Cancer/Testis Antigen 1.1;
- Gene ID
- 4100
- UniProt ID
- P43355
Downloads
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See other products for "MAGEA1"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1637z | Mouse Anti-MAGEA1 Recombinant Antibody (clone 33D1) | FC, IF, IHC | Mouse IgG1, κ |
| MOB-1121CT | Recombinant Mouse anti-Human MAGEA1 Monoclonal antibody (NB565) | WB | |
| HPAB-M0143-YC | Human Anti-MAGEA1 Recombinant Antibody (clone M/YC-15) | ELISA, WB | Human IgG |
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G048A | Anti-MAGEA1 immunotoxin (scFv)-ABR | Cytotoxicity assay, Function study |
MHC Tetramer for Cancer
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2122 | Hi-Affi™ Recombinant Rabbit Anti-MAGEA1 Monoclonal Antibody (DS2122AB) | WB, ICC, FC | IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0143-YC-S(P) | Human Anti-MAGEA1 Recombinant Antibody (clone M/YC-15); scFv Fragment | ELISA, WB | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0143-YC-F(E) | Human Anti-MAGEA1 Recombinant Antibody (clone M/YC-15); Fab Fragment | ELISA, WB | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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