A*02:01/Human PSM P2 (ALFDIESKV) MHC Pentamer (CAT#: MHC-YF699)
MHC pentamers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a MHC pentamer of peptide/MHC complex composed PSM P2-derived peptide of ALFDIESKV sequence and A*02:01 molecule. The peptide/MHC pentamer provided here is unlabelled or fluorescent labelled, such as Biotin, R-PE, APC. All products are available in 50, 150 and 500 tests.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Kidney
(Proximal tubules (microvilli)
Staining: High
Intensity: Strong)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1451/4354_A_7_5.jpg
(Proximal tubules (microvilli)
Staining: High
Intensity: Strong)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1451/4354_A_7_5.jpg
Figure 2 Prostate
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1451/4354_A_2_5.jpg
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1451/4354_A_2_5.jpg
Figure 3 RNA cell line category: Cell line enhanced (HAP1, RPMI-8226, SK-BR-3, TIME, WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000086205-FOLH1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000086205-FOLH1
Figure 3 RNA cell line category: Cell line enhanced (HAP1, RPMI-8226, SK-BR-3, TIME, WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000086205-FOLH1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000086205-FOLH1
Specifications
- Allele
- A*02:01
- Class
- Class I
- Antigen
- PSM P2
- Antigen Species
- Human
- Peptide
- ALFDIESKV
- Conjugate
- Unlabeled, Biotin, R-PE, APC
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms. [provided by RefSeq, Jul 2010]
- Alternative Names
- Folate Hydrolase 1; N-Acetylated-Alpha-Linked Acidic Dipeptidase I; Pteroylpoly-Gamma-Glutamate Carboxypeptidase; Folylpoly-Gamma-Glutamate Carboxypeptidase; Cell Growth-Inhibiting Gene 27 Protein; Membrane Glutamate Carboxypeptidase; Glutamate Carboxypeptidase II; Glutamate Carboxypeptidase 2; Glutamate Carboxylase II; EC 3.4.17.21; NAALADase I; NAALAD1; GCPII;
- Gene ID
- 2346
- UniProt ID
- Q04609
Downloads
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See other products for "FOLH1"
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABG-066 | Recombinant Anti-Human FOLH1 VHH Single Domain Antibody | ELISA, IHC, FC, FuncS | Llama VHH |
| TAB-277CT | Anti-Human PSMA Therapeutic Single Domain Single Domain Antibody (TAB-277CT) | ELISA | Single domain antibody |
| HPAB-M0386-YC | Recombinant Camelid Anti-FOLH1 Single Domain Antibody (HPAB-M0386-YC) | ELISA | Camelid VHH |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-018 | Anti-Human PMSA Recombinant Antibody (Capromab Pendetide) | ELISA, FC, IP, FuncS, IF, Neut, WB | IgG1 - kappa |
| TAB-274CT | Mouse Anti-FOLH1 Recombinant Antibody (TAB-274CT) | FC, IA, IHC, Inhib, IB, IF, WB, ELISA | Mouse IgG2a |
| TAB-275CT | Mouse Anti-FOLH1 Recombinant Antibody (TAB-275CT) | ICC, FC, Block, IB, IF, IHC, Inhib, WB, ELISA | Mouse IgG1 |
| TAB-276CT | Mouse Anti-FOLH1 Recombinant Antibody (TAB-276CT) | IB, FC, IF, Inhib, WB, ELISA, IHC | Mouse IgG2b |
| TAB-289CT-S(P) | Mouse Anti-FOLH1 Recombinant Antibody; scFv Fragment (TAB-289CT-S(P)) | ELISA, FC | Mouse scFv |
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G029E | Anti-FOLH1 immunotoxin D7 (scFv)-PE | Cytotoxicity assay, Function study | |
| AGTO-G029D | Anti-FOLH1 immunotoxin D7 (scFv)-DT | Cytotoxicity assay, Function study |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1332 | Hi-Affi™ Rabbit Anti-FOLH1 Recombinant Antibody (clone DS1332AB) | IHC-P | Rabbit IgG |
MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC3286 | PE-A*24:02/Human FOLH1 (FYDPMFKYHL) MHC Tetramer | FCM | |
| MHC-LC3287 | PE-A*24:02/Human FOLH1 (KYADKIYSI) MHC Tetramer | FCM | |
| MHC-CN0089 | APC-B*27:05/Human PSMA (FRGNKVKNA) MHC Tetramer | FCM | |
| MHC-CN0090 | PE-B*27:05/Human PSMA (FRGNKVKNA) MHC Tetramer | FCM | |
| MHC-YF054 | DRB1*04:01/Human PSMA (NYTLRVDCTPLMYSL) MHC Monomer | MHC Multimer |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0656-CN | Mouse Anti-FOLH1 Recombinant Antibody (HPAB-0656-CN) | WB, IF, FC | Mouse IgG1 |
| HPAB-N0091-YC | Human Anti-FOLH1 Recombinant Antibody (HPAB-N0091-YC) | ELISA, FC, FuncS, Block | Human IgG |
| HPAB-N0092-YC | Human Anti-FOLH1 Recombinant Antibody (HPAB-N0092-YC) | ELISA, FC | Human IgG1, κ |
| HPAB-1248WJ | Human Anti-FOLH1 Recombinant Antibody (clone 3D8) | FC | Human IgG |
| HPAB-1249WJ | Human Anti-FOLH1 Recombinant Antibody (clone 4D4) | ELISA | Human IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0184CQ-S(P) | Human Anti-FOLH1 Recombinant Antibody (clone 2A10); scFv Fragment | ELISA, FC | Human scFv |
| HPAB-M0092-YC-S(P) | Mouse Anti-FOLH1 Recombinant Antibody (clone 10B3); scFv Fragment | FC | Mouse scFv |
| HPAB-M0093-YC-S(P) | Human Anti-FOLH1 Recombinant Antibody (clone h10B3); scFv Fragment | FC | Humanized scFv |
| HPAB-1708-FY-F(E) | Human Anti-FOLH1 Recombinant Antibody; Fab Fragment (HPAB-1708-FY-F(E)) | Cyt | Human Fab |
| HPAB-1710-FY-F(E) | Human Anti-FOLH1 Recombinant Antibody; Fab Fragment (HPAB-1710-FY-F(E)) | Cyt | Human Fab |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-018 | Afuco™ Anti-FOLH1 ADCC Recombinant Antibody (Capromab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0092-YC-F(E) | Mouse Anti-FOLH1 Recombinant Antibody (clone 10B3); Fab Fragment | FC | Mouse Fab |
| HPAB-M0093-YC-F(E) | Human Anti-FOLH1 Recombinant Antibody (clone h10B3); Fab Fragment | FC | Humanized Fab |
| HPAB-1708-FY-S(P) | Human Anti-FOLH1 Recombinant Antibody; scFv Fragment (HPAB-1708-FY-S(P)) | Cyt | Human scFv |
| HPAB-1710-FY-S(P) | Human Anti-FOLH1 Recombinant Antibody; scFv Fragment (HPAB-1710-FY-S(P)) | Cyt | Human scFv |
| HPAB-J0213-YC-F(E) | Mouse Anti-FOLH1 Recombinant Antibody; Fab Fragment (HPAB-J0213-YC-F(E)) | ELISA, IHC (0.3µg/mL), FuncS | Mouse Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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