APC-A*02:01/Human Cyclin D1 (LLNDRVLRV) MHC Tetramer (CAT#: MHC-CN0165)


Specific Inquiry
  • Size:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Normal Tissue
RNA Expression

Specifications

  • Allele
  • A*02:01
  • Class
  • Class I
  • Antigen
  • Cyclin D1
  • Antigen Species
  • Human
  • Peptide
  • LLNDRVLRV
  • Conjugate
  • APC
  • Application
  • FCM

Target

  • Antigen Introduction
  • The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis. [provided by RefSeq, Jul 2008]
  • Alternative Names
  • CCND1; Parathyroid Adenomatosis 1; G1/S-Specific Cyclin-D1; Cyclin D1 (PRAD1: Parathyroid Adenomatosis 1); PRAD1; B-Cell Lymphoma 1 Protein; D11S287E; U21B31

Related Resources

  • Related Diseases
  • Related Signaling Pathways

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "CCND1"

Immunotoxin

CAT Product Name Application Type
AGTO-G004R Anti-Ccnd1 immunotoxin (IgG)-RTA Cytotoxicity assay, Function study

Blocking Antibody

CAT Product Name Application Type
NEUT-262CQ Mouse Anti-CCND1 Recombinant Antibody (clone DCS-6) IHC-Fr, WB, Block, IHC-P, IF, FC, IP Mouse IgG2a, κ

Rabbit Monoclonal Antibody

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