A*24:02/Human VEGFR (SYGVLLWEI) MHC Monomer (CAT#: MHC-YF304)

This product is a MHC monomer of biotinylated peptide/MHC complex composed VEGFR-derived peptide of SYGVLLWEI sequence and A*24:02 molecule. The pMHC monomer recognizes human CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.


Specific Inquiry
  • Size:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Normal Tissue
RNA Expression

Specifications

  • Allele
  • A*24:02
  • Class
  • Class I
  • Antigen
  • VEGFR
  • Antigen Species
  • Human
  • Peptide
  • SYGVLLWEI
  • Conjugate
  • Biotin
  • Application
  • MHC Multimer

Target

  • Antigen Introduction
  • Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.
  • Alternative Names
  • FLK1; CD309; VEGFR; VEGFR2

Downloads

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Humanized Antibody

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Immunotoxin

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Chicken IgY Antibody

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Single-domain Antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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