This immunotoxin was achieved by conjugating/fusing the aFGF to Pseudomonas exotoxin. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to epidermoid carcinoma cells and enters cells by receptor-mediated endocytosis, then PE cleaved fragments the size of Mr 37000 and 27000, the large fragment and finally into the Golgi and elongation factor 2 (EM) combining it glycosylation inactivation, inhibition of protein synthesis, leading to apoptosis. It was designed for treatment of epidermoid carcinoma.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1249z | Mouse Anti-FGFR3 Recombinant Antibody (clone 3F6) | WB, ELISA, FC | Mouse IgG2a |
HPAB-0150-WJ | Human Anti-FGFR3 Recombinant Antibody (HPAB-0150-WJ) | ELISA | Human IgG1 |
VS3-XY705 | Mouse Anti-FGFR3 Recombinant Antibody (clone 2H2C4) | ELISA, WB | Mouse IgG2a |
VS3-XY706 | Mouse Anti-FGFR3 Recombinant Antibody (clone 4B6G10) | ELISA, WB, IHC, FC | Mouse IgG1 |
VS3-XY707 | Mouse Anti-FGFR3 Recombinant Antibody (clone 9E12D9) | ELISA, WB, IHC, FC | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
AGTO-G028E | Anti-FGFR3 immunotoxin (scFv)-PE | Cytotoxicity assay, Function study | |
AGTO-G028G | Anti-FGFR3 immunotoxin (scFv)-Gel | Cytotoxicity assay, Function study | |
AGTO-L016G | aFGF-Gel immunotoxin | Cytotoxicity assay, Functional assay |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBL-471 | Human Anti-FGFR3 Recombinant Antibody (clone R3Mab); Fab Fragment | ELISA | Human Fab |
HPAB-0157-YC-F(E) | Human Anti-FGFR3 Recombinant Antibody; Fab Fragment (HPAB-0157-YC-F(E)) | ELISA, IP, WB | Human Fab |
HPAB-0158-YC-F(E) | Mouse Anti-FGFR3 Recombinant Antibody; Fab Fragment (HPAB-0158-YC-F(E)) | ELISA, FC | Mouse Fab |
HPAB-0159-YC-F(E) | Human Anti-FGFR3 Recombinant Antibody (clone Antibody 1); Fab Fragment | ELISA, FuncS | Human Fab |
HPAB-0160-YC-F(E) | Human Anti-FGFR3 Recombinant Antibody (clone PRO-001); Fab Fragment | FC, FuncS | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBW-162 | Human Anti-FGFR3 Recombinant Antibody (clone R3); Fab Fragment | Neut, ELISA, FC | Human Fab |
HPAB-0157-YC-S(P) | Human Anti-FGFR3 Recombinant Antibody; scFv Fragment (HPAB-0157-YC-S(P)) | ELISA, IP, WB | Human scFv |
HPAB-AP654-YC-S(P) | Human Anti-FGFR3 Recombinant Antibody; scFv Fragment (HPAB-AP654-YC-S(P)) | ELISA, Inhib, FuncS | Human scFv |
HPAB-AP655-YC-S(P) | Human Anti-FGFR3 Recombinant Antibody; scFv Fragment (HPAB-AP655-YC-S(P)) | ELISA, Inhib, FuncS | Human scFv |
HPAB-AP656-YC-S(P) | Human Anti-FGFR3 Recombinant Antibody; scFv Fragment (HPAB-AP656-YC-S(P)) | ELISA, Inhib, FuncS | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-062WM | Mouse Anti-FGFR3 Recombinant Antibody (TAB-062WM) | ELISA, FC, Neut, WB | Mouse IgG |
TAB-063WM | Mouse Anti-FGFR3 Recombinant Antibody (TAB-063WM) | ELISA, FC, Neut, WB | Mouse IgG |
TAB-064WM | Anti-Human FGFR3 Recombinant Antibody (15D8) | Neut, ELISA | |
TAB-062WM-S(P) | Mouse Anti-FGFR3 Recombinant Antibody; scFv Fragment (TAB-062WM-S(P)) | ELISA, FC, Neut, WB | Mouse scFv |
TAB-063WM-S(P) | Mouse Anti-FGFR3 Recombinant Antibody; scFv Fragment (TAB-063WM-S(P)) | ELISA, FC, Neut, WB | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-834CQ | Mouse Anti-FGFR3 Recombinant Antibody (clone CBL546) | Neut | Mouse IgG1 |
NEUT-835CQ | Mouse Anti-FGFR3 Recombinant Antibody (clone CBL547) | WB, Neut | Mouse IgG1 |
NEUT-836CQ | Mouse Anti-FGFR3 Recombinant Antibody (clone 6G11) | WB, Neut | Mouse IgG1 |
NEUT-837CQ | Mouse Anti-FGFR3 Recombinant Antibody (clone CBL061) | WB, IHC, Neut | Mouse IgG1 |
NEUT-838CQ | Rat Anti-Fgfr3 Recombinant Antibody (clone CBL548) | Neut | Rat IgG2a |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1299 | Hi-Affi™ Rabbit Anti-FGFR3 Recombinant Antibody (clone DS1299AB) | WB, IHC, ICC, FC | Rabbit IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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