This product is a recombinant antibody that recognizes α5β1. The monoclonal antibody M200 reacts with the epitope of α5β1.
Figure 1 Illustrates results of M200 is a potent inhibitor of endothelial cell growth, encompassing the anti-proliferative properties of an anti-VEGF mAb, HuMV833.
Figure 2 Illustrates results showing that M200 inhibits VEGF induced cell growth.
Figure 3 Illustrates results showing: quantification of annexin stained cells by flow cytometry.
Figure 4 Illustrates results showing M200 causes increased cell death in proliferating versus senescent HUVEC.
Figure 5 Depicts results of a competition ELISA binding assay comparing binding affinities of mouse antibody IIA1, chimeric antibody M200 (200-4 EOS), and two humanized versions of M200: huM200-G4 and huM200-g2m3G.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1059 | Recombinant Anti-α5β1 Antibody | WB, IF, FuncS | IgG |
PABL-748 | Mouse Anti-α5β1 Recombinant Antibody (clone SG/19) | WB, ELISA, FuncS | Mouse IgG |
HPAB-0023-YJ | Human Anti-α5β1 Recombinant Antibody (HPAB-0023-YJ) | FuncS | Chimeric (mouse/human) IgG |
HPAB-0049-YJ | Mouse Anti-α5β1 Recombinant Antibody (clone B9) | ELISA, Neut, IHC, FC, Inhib | Mouse IgG1, κ |
HPAB-2115-FY | Human Anti-α5β1 Recombinant Antibody (clone 2H12) | Inhib, ELISA | Human IgG4 |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0023-YJ-F(E) | Human Anti-α5β1 Recombinant Antibody; Fab Fragment (HPAB-0023-YJ-F(E)) | FuncS | Chimeric (mouse/human) Fab |
HPAB-0049-YJ-F(E) | Mouse Anti-α5β1 Recombinant Antibody (clone B9); Fab Fragment | ELISA, Neut, IHC, FC, Inhib | Mouse Fab |
HPAB-0420-YJ-F(E) | Human Anti-α5β1 Recombinant Antibody (clone MOR04974); Fab Fragment | ELISA, IP, FC, IHC, Block, FuncS | Human Fab |
HPAB-0421-YJ-F(E) | Human Anti-α5β1 Recombinant Antibody (clone MOR04977); Fab Fragment | ELISA, IP, FC, IHC, Block, FuncS | Human Fab |
HPAB-2115-FY-F(E) | Human Anti-α5β1 Recombinant Antibody (clone 2H12); Fab Fragment | Inhib, ELISA | Human Fab4 |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-1869-FY-F(E) | Mouse Anti-α5β1 Recombinant Antibody (clone 11A1); scFv Fragment | ELISA | Mouse scFv |
HPAB-1870-FY-F(E) | Mouse Anti-α5β1 Recombinant Antibody (clone 200-4); scFv Fragment | ELISA | Mouse scFv |
HPAB-1871-FY-F(E) | Mouse Anti-α5β1 Recombinant Antibody (clone F200); scFv Fragment | ELISA, Inhib | Mouse scFv |
HPAB-1872-FY-F(E) | Human Anti-α5β1 Recombinant Antibody (clone huM200); scFv Fragment | ELISA, Inhib | Human scFv |
HPAB-1873-FY-F(E) | Mouse Anti-α5β1 Recombinant Antibody (clone M200); scFv Fragment | ELISA, Inhib | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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