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Rabbit Anti-AGPS Recombinant Antibody (clone R04-3C4) (CAT#: VS3-FY1644)

This is a rabbit recombinant antibody that has the application function of IHC. The antibody is specifically engineered to detect human AGPS. Western blot demonstrated that R04-3C4 recognized a target protein with a molecular weight of 73 kDa.


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Specific Inquiry
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  • Purity:
  • Fc Engineering:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to peroxisomes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30209/320_H7_1_selected.jpg
Figure 2 IF staining of human cell line A-431
Figure 2 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoli & peroxisomes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30211/560_D9_1_selected.jpg
Normal Tissue
Figure 3 IHC staining of human caudate
Figure 3 IHC staining of human caudate
(Immunohistochemical staining of human caudate shows strong cytoplasmic positivity in neuronal cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30209/ihc_selected.jpg
Figure 4 IHC staining of human pancreas
Figure 4 IHC staining of human pancreas
(Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in subsets of islet cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30211/ihc_selected.jpg
Figure 5 Testis
Figure 5 Testis
(Sertoli cells Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30210/66883_A_4_6.jpg
Figure 6 Epididymis
Figure 6 Epididymis
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30210/66883_A_1_6.jpg
Figure 7 Colon
Figure 7 Colon
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30210/66883_A_8_3.jpg
RNA Expression
Figure 8 RNA cell line category: Low cell line specificity
Figure 8 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000018510-AGPS

Specifications

  • Immunogen
  • Recombinant human alkyl-DHAP synthase protein
  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human AGPS
  • Species Reactivity
  • Human
  • Clone
  • R04-3C4
  • Applications
  • Western Blot, Immunohistochemistry-Paraffin, Immunoprecipitation
  • MW
  • The calculated weight of the target protein is approximately 73 kDa, while the observed molecular weight stands at 73 kDa.
  • Related Disease
  • Rhizomelic Chondrodysplasia Punctata, Type 3 and Rhizomelic Chondrodysplasia Punctata

Product Property

  • Purification
  • Affinity Purified
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • Western Blot: 1/500-1/1000
    Immunohistochemistry: 1/50-1/100
    Immunoprecipitation: 1/20

Target

  • Alternative Names
  • Alkylglycerone Phosphate Synthase; Aging-Associated Gene 5 Protein; Alkyl-DHAP Synthase; EC 2.5.1.26; Alkyldihydroxyacetonephosphate Synthase, Peroxisomal; Alkylglycerone-Phosphate Synthase; Aging-Associated Protein 5
  • Sequence Similarities
  • Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
  • Cellular Localization
  • Membrane, Peroxisome
  • Post Translation Modifications
  • Acetylation, Phosphoprotein
  • Function
  • Catalyzes the exchange of the acyl chain in acyl-dihydroxyacetonephosphate (acyl-DHAP) for a long chain fatty alcohol, yielding the first ether linked intermediate, i.e. alkyl-dihydroxyacetonephosphate (alkyl-DHAP), in the pathway of ether lipid biosynthesis.

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "AGPS"

Recombinant Antibody

CAT Product Name Application Type
MOB-2236z Mouse Anti-AGPS Recombinant Antibody (clone 21B10) WB, ELISA, IF, IP Mouse IgG1, κ

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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