Mouse Anti-ALB Recombinant Antibody (VS3-CJ61) (CAT#: VS3-CJ61)

• Immunogen
• Human albumin (ALB)

• Host Species
• Mouse

• Type
• Mouse IgG

• Specificity
• Human ALB

• Species Reactivity
• Human

• Applications
• WB, ELISA

• Conjugate
• Unconjugated

• Purification
• Protein G affinity purified

• Purity
• >95% as determined by SDS-PAGE

• Format
• Liquid

• Concentration
• 1 mg/mL (lot specific)

• Buffer
• 50% Glycerol, 1% BSA, PBS, pH7.4.

• Preservative
• 0.02% sodium azide

• Storage
• Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

• Shipping
• Ice packs

• Application Notes
• This antibody has been tested for use in ELISA (1:5000-1:20000), Western Blot (1:100-1:2000).

• Alternative Names
• FDAHT; HSA; PRO0883; PRO0903; PRO1341

• Gene ID
• 213

• UniProt ID
• P02768

• Sequence Similarities
• Belongs to the ALB/AFP/VDB family.

• Cellular Localization
• Secreted

• Post Translation Modifications
• Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.
  Glycated in diabetic patients.
  Phosphorylated by FAM20C in the extracellular medium.
  Acetylated on Lys-223 by acetylsalicylic acid.

• Protein Refseq
• NP_000468.1

• Function
• Binds water, Ca2+, Na+, K+, fatty acids, hormones, bilirubin and drugs (Probable). Its main function is the regulation of the colloidal osmotic pressure of blood (Probable). Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (PubMed:19021548).
  Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity).
  Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (By similarity).
  The shared binding site between zinc and calcium at residue Asp-273 suggests a crosstalk between zinc and calcium transport in the blood (By similarity).
  The rank order of affinity is zinc> calcium> magnesium (By similarity).
  Binds to the bacterial siderophore enterobactin and inhibits enterobactin-mediated iron uptake of E.coli from ferric transferrin, and may thereby limit the utilization of iron and growth of enteric bacteria such as E.coli (PubMed:6234017).
  Does not prevent iron uptake by the bacterial siderophore aerobactin (PubMed:6234017).

Isotype Control

• MRO-A1591-YJ
• Mouse IgG Isotype control, Polyclonal

Secondary Antibody

• 2ND-040CQ
• Goat Anti-Mouse IgG (H&L) Antibody

• 2ND-042CQ
• Rabbit Anti-Mouse IgG (H&L) Antibody

Recommended Dilution Buffer

• MRO-0253YJ
• Reconstitution Buffer PBS