Rabbit Anti-BGN Recombinant Antibody (clone R07-4G6) (CAT#: VS3-XY3277)
The antibody is a recombinant rabbit antibody against BGN (Biglycan), which may be involved in collagen fiber assembly. The molecular weight of this antibody is about 42 kDa. It specifically reacts with human, mouse and rat BGN. This product has been reported for use in Western Blot, Immunoprecipitation and Flow cytometry.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line BJ
(Immunofluorescent staining of human cell line BJ shows localization to endoplasmic reticulum & the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3157/1742_D5_7_cr5804956327650_selected.jpg
(Immunofluorescent staining of human cell line BJ shows localization to endoplasmic reticulum & the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3157/1742_D5_7_cr5804956327650_selected.jpg
Figure 2 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3678/10249_A_9_4.jpg
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3678/10249_A_9_4.jpg
Figure 3 Kidney
(Cells in glomeruli Staining: Medium Intensity: Strong Quantity: <25% Collecting ducts Staining: Low Intensity: Moderate Quantity: <25% Distal tubules Staining: Low Intensity: Moderate Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3678/10249_A_9_5.jpg
(Cells in glomeruli Staining: Medium Intensity: Strong Quantity: <25% Collecting ducts Staining: Low Intensity: Moderate Quantity: <25% Distal tubules Staining: Low Intensity: Moderate Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3678/10249_A_9_5.jpg
Figure 4 High expression in placenta
(Syncytiotrophoblasts - cell body Staining: High Intensity: Strong Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3678/10249_A_3_7.jpg
(Syncytiotrophoblasts - cell body Staining: High Intensity: Strong Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3678/10249_A_3_7.jpg
Figure 5 RNA cell line category: Cell line enhanced (BJ, BJ hTERT+, fHDF/TERT166, HSkMC, hTEC/SVTERT24-B, HUVEC TERT2, U-138 MG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000182492-BGN
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000182492-BGN
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat BGN
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R07-4G6
- Applications
- WB, IP, FC
- Related Disease
- Meester-Loeys syndrome (MRLS)
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IP: 1/20
FC: 1/50-1/100
Target
- Alternative Names
- PGI; MRLS; DSPG1; PG-S1; SEMDX; SLRR1A
- Gene ID
- 633
- UniProt ID
- P21810
- Long Name
- Biglycan
- Cellular Localization
- Extracellular matrix, Secreted
- Post Translation Modifications
- The two attached glycosaminoglycan chains can be either chondroitin sulfate or dermatan sulfate.
- Protein Refseq
- XP_054183538.1; XP_016885213.1
- Function
- May be involved in collagen fiber assembly.
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "BGN"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2941z | Mouse Anti-BGN Recombinant Antibody (clone 18G12) | WB, ELISA, IHC, IP | Mouse IgG2a, κ |
| MOB-2268MZ | Mouse Anti-BGN Recombinant Antibody (clone CBLS-199) | FC, IF, IHC-P, WB | Mouse IgG2a |
| MRO-0180-CN | Rabbit Anti-BGN Recombinant Antibody (clone JB71-31) | WB, IHC, FC, IP | Rabbit IgG |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0354 | Hi-Affi™ Rabbit Anti-BGN Recombinant Antibody (clone DS354AB) | WB, IP, FC | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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