Mouse Anti-BID Recombinant Antibody (VS3-CJ1050) (CAT#: VS3-CJ1050)
This product is a mouse antibody that recognizes human BID.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/722/if_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/722/if_selected.jpg
Figure 2 Bone marrow
(Hematopoietic cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3771/10351_B_4_4.jpg
(Hematopoietic cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3771/10351_B_4_4.jpg
Figure 3 Lymph node
(Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3771/10351_A_8_8.jpg
(Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3771/10351_A_8_8.jpg
Figure 4 Colon
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3771/10351_A_9_3.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3771/10351_A_9_3.jpg
Figure 5 RNA cell line category: Cell line enhanced (MCF7)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000015475-BID
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000015475-BID
Specifications
- Immunogen
- Recombinant protein of human BID
- Host Species
- Mouse
- Type
- Mouse IgG1, κ
- Specificity
- Human BID
- Species Reactivity
- Human
- Applications
- WB, ICC, IHC
- Conjugate
- Unconjugated
Product Property
- Purification
- Affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- PBS
- Preservative
- 0.09% Sodium Azide
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Western Blot (1:4000), Immunocytochemistry (1:25), Immunohistochemistry (1:25).
Target
- Alternative Names
- FP497
- Gene ID
- 637
- UniProt ID
- P55957
- Cellular Localization
- Cytoplasm, Membrane, Mitochondrion, Mitochondrion outer membrane
- Post Translation Modifications
- BH3-interacting domain death agonist:
TNF-alpha induces caspase-mediated cleavage into a major p15 and minor p13 and p11 products (By similarity).
Cleaved by CASP6 into a major p15 and minor p13 products, leading to release of cytochrome c and subsequent nonalcoholic steatohepatitis (PubMed:32029622).
BH3-interacting domain death agonist p15:
Ubiquitinated by ITCH; ubiquitination results in proteasome-dependent degradation.
- Protein Refseq
- NP_001187.1; NP_001231496.1; NP_001231498.1
- Function
- Induces caspases and apoptosis (PubMed:14583606).
Counters the protective effect of BCL2 (By similarity).
BH3-interacting domain death agonist p15
Induces caspase activation and apoptosis (PubMed:15661737, PubMed:32029622).
Allows the release of cytochrome c (PubMed:32029622).
Isoform 1: Induces ICE-like proteases and apoptosis.1 Publication
Isoform 2: Induces ICE-like proteases and apoptosis.
Isoform 3: Does not induce apoptosis.
Isoform 4: Induces ICE-like proteases and apoptosis.
Recommended Products
Secondary Antibody
Recommended Dilution Buffer
Related Resources
p53 Signaling Pathway
Amyotrophic Lateral Sclerosis
Maturity Onset Diabetes of the Young
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "BID"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2323z | Mouse Anti-BID Recombinant Antibody (clone 19H5) | WB, ELISA, FC, IF, IHC | Mouse IgG1 |
| MOB-2266MZ | Mouse Anti-BID Recombinant Antibody (clone 4D6) | ELISA, FC, IF, IHC-P, WB | Mouse IgG1 |
| MRO-0179-CN | Rabbit Anti-BID Recombinant Antibody (clone JM11-14) | WB, IF, IHC, FC, IP | Rabbit IgG |
| VS3-FY1976 | Rabbit Anti-BID Recombinant Antibody (clone R08-2F0) | WB, IHC-Fr, IHC-P, IF, IP | Rabbit IgG |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0356 | Hi-Affi™ Rabbit Anti-BID Recombinant Antibody (clone DS356AB) | FC, IF, IHC-P, IP, WB | Rabbit IgG |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for VS3-CJ1050. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.