Recombinant Ovine Anti-BoNT/A Antibody (scFV2) (CAT#: FAMAB-0272-CN)
This is a sheep neutralizing monoclonal antibody that specifically reacts with BoNT/A. The scFv2 is capable of producing detectable toxin neutralization.
Specific Inquiry
Neut
Figure 1 Dose-response curve of BoNT/A neutralization by anti-BoNT/A scFv 2.
BoNT/A (0.1 nM) and various dilutions of scFv 2, as indicated, were mixed and added to neuronal cell cultures for 3 h prior to Western blotting for SNAP25. Toxin neutralization was assessed by inhibition of SNAP25 cleavage by BoNT/A as described above.
Sepulveda, J., Mukherjee, J., Tzipori, S., Simpson, L. L., & Shoemaker, C. B. (2010). Efficient serum clearance of botulinum neurotoxin achieved using a pool of small antitoxin binding agents. Infection and immunity, 78(2), 756-763.
Specifications
- Immunogen
- Recombinant BoNT/A1 heavy chain carboxyl end (A-HC)
- Host Species
- Ovine
- Derivation
- Phage display library
- Type
- Ovine IgG
- Specificity
- BoNT/A
- Clone
- scFV2
- Applications
- WB, ELISA, BL, Neut
Product Property
- Storage
- Store at -20°C for long-term storage. Avoid freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Enzyme-Linked Immunosorbent Assay, Western Blot, Blocking and Neutralization.
Target
- Alternative Names
- BoNT/A
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0257-CN | Recombinant Human Anti-BoNT/A Antibody (C10) | Block, Neut | Human IgG4 |
| FAMAB-0258-CN | Recombinant Human Anti-BoNT/A Antibody (1B6) | Block, Neut | Human IgG4 |
| FAMAB-0270-CN | Recombinant Ovine Anti-BoNT/A Antibody (scFV7) | WB, ELISA, BL | Ovine IgG |
| FAMAB-0271-CN | Recombinant Ovine Anti-BoNT/A Antibody (scFV3) | WB, ELISA, BL | Ovine IgG |
| HPAB-0163-WJ | Recombinant Mouse Anti-BoNT/A Antibody (FMU-BTA49) | ELISA | Mouse IgG1, κ |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0257-CN-F(E) | Recombinant Human Anti-BoNT/A Antibody Fab Fragment (C10) | ELISA, BL | Human Fab |
| FAMAB-0258-CN-F(E) | Recombinant Human Anti-BoNT/A Antibody Fab Fragment (1B6) | ELISA, BL | Human Fab |
| FAMAB-0270-CN-F(E) | Recombinant Ovine Anti-BoNT/A Antibody Fab Fragment (scFV7) | WB, ELISA, BL | Ovine Fab |
| FAMAB-0271-CN-F(E) | Recombinant Ovine Anti-BoNT/A Antibody Fab Fragment (scFV3) | WB, ELISA, BL | Ovine Fab |
| FAMAB-0272-CN-F(E) | Recombinant Ovine Anti-BoNT/A Antibody Fab Fragment (scFV2) | WB, ELISA, BL | Ovine Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0163-WJ-S(P) | Recombinant Mouse Anti-BoNT/A Antibody scFv Fragment (FMU-BTA49) | ELISA | Mouse scFv |
| HPAB-1010-FY-F(E) | Mouse Anti-BONT/A Recombinant Antibody; Fab Fragment (HPAB-1010-FY-F(E)) | WB, ELISA | Mouse Fab |
| HPAB-1011-FY-F(E) | Mouse Anti-BONT/A Recombinant Antibody; Fab Fragment (HPAB-1011-FY-F(E)) | WB, ELISA | Mouse Fab |
| HPAB-1012-FY-F(E) | Human Anti-BONT/A Recombinant Antibody; Fab Fragment (HPAB-1012-FY-F(E)) | Neut | Human Fab |
| HPAB-1099WJ-S(P) | Recombinant Human Anti-BoNT/A Antibody scFv Fragment (ABT01) | ELISA | Humanized scFv |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABJ-0046 | Camelid Anti-BoNT/A Recombinant Antibody (PABJ-0046) | ELISA | Camelid VHH |
| PABJ-0047 | Camelid Anti-BoNT/A Recombinant Antibody (PABJ-0047) | ELISA | Camelid VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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