This product is a camelid single domain antibody specifically bind BoNT A complex in toxoid and untoxoided forms. This antibody can be used in applications, such as ELISA, WB, Neut.
Figure 1 Specificity and ranking of anti-BoNT A complex sdAb clones on bead immobilized targets.
The binding curves of the sdAb binding to BoNT A complex toxoid coated beads with sdAb concentration shown on a log and linear scale respectively.
Goldman ER, Anderson GP, Conway J, Sherwood LJ, Fech M, Vo B, Liu JL, Hayhurst A. Thermostable llama single domain antibodies for detection of botulinum A neurotoxin complex. Anal Chem. 2008 Nov 15;80(22):8583-91.
Figure 2 Western blotting of sdAb clones.
The toxin complex western blotted and probed with each of the sdAb clones or no sdAb (-ve) as fusions to hyperactive alkaline phosphatase, all appearing to bind a 33 kDa species.
Goldman ER, Anderson GP, Conway J, Sherwood LJ, Fech M, Vo B, Liu JL, Hayhurst A. Thermostable llama single domain antibodies for detection of botulinum A neurotoxin complex. Anal Chem. 2008 Nov 15;80(22):8583-91.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
NAB-1537-sdAb | Recombinant Anti-C. botulinum BoNT/A VHH Single Domain Antibody | FUNC, FA, IP, ChiP | Llama VHH |
HPAB-0684-YJ-VHH | Camelid Anti-C. botulinum BoNT/A Recombinant Single Domain Antibody (HPAB-0684-YJ-VHH) | ELISA, Neut | Camelid VHH |
HPAB-0685-YJ-VHH | Camelid Anti-C. botulinum BoNT/A Recombinant Single Domain Antibody (HPAB-0685-YJ-VHH) | ELISA | Camelid VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-1967-FY | Human Anti-C. botulinum BoNT/A Recombinant Antibody (clone 4LCA) | Inhib, IF | Human IgG1, λ |
HPAB-S0007-YC | Human Anti-C. botulinum BoNT/A Recombinant Antibody (clone 1B6) | ELISA, IF, Neut, FuncS | Humanized IgG |
HPAB-S0008-YC | Human Anti-C. botulinum BoNT/A Recombinant Antibody (clone C10) | ELISA, IF, Neut, FuncS | Humanized IgG4 |
FAMAB-0116WJ | Mouse Anti-C. botulinum BoNT/A Recombinant Antibody (clone S25) | ELISA, WB, Neut | Mouse IgG1, κ |
FAMAB-0117WJ | Mouse Anti-C. botulinum BoNT/A Recombinant Antibody (clone C25) | ELISA, WB, Neut | Mouse IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-1967-FY-S(P) | Human Anti-C. botulinum BoNT/A Recombinant Antibody (clone 4LCA); scFv Fragment | Inhib, IF | Human scFv |
HPAB-S0007-YC-S(P) | Human Anti-C. botulinum BoNT/A Recombinant Antibody (clone 1B6); scFv Fragment | ELISA, IF, Neut, FuncS | Humanized scFv |
HPAB-S0008-YC-S(P) | Human Anti-C. botulinum BoNT/A Recombinant Antibody (clone C10); scFv Fragment | ELISA, IF, Neut, FuncS | Humanized scFv |
FAMAB-0116WJ-S(P) | Mouse Anti-C. botulinum BoNT/A Recombinant Antibody (clone S25); scFv Fragment | ELISA, WB, Neut | Mouse scFv |
FAMAB-0117WJ-S(P) | Mouse Anti-C. botulinum BoNT/A Recombinant Antibody (clone C25); scFv Fragment | ELISA, WB, Neut | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0116WJ-F(E) | Mouse Anti-C. botulinum BoNT/A Recombinant Antibody (clone S25); Fab Fragment | ELISA, WB, Neut | Mouse Fab |
FAMAB-0117WJ-F(E) | Mouse Anti-C. botulinum BoNT/A Recombinant Antibody (clone C25); Fab Fragment | ELISA, WB, Neut | Mouse Fab |
FAMAB-0118WJ-F(E) | Mouse Anti-C. botulinum BoNT/A Recombinant Antibody (clone 3D12); Fab Fragment | ELISA, WB, Neut | Mouse Fab |
FAMAB-0119WJ-F(E) | Mouse Anti-C. botulinum BoNT/A Recombinant Antibody (clone B4); Fab Fragment | ELISA, WB, Neut | Mouse Fab |
FAMAB-0120WJ-F(E) | Mouse Anti-C. botulinum BoNT/A Recombinant Antibody (clone 7C1); Fab Fragment | ELISA, WB, Neut | Mouse Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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