2E10 is a recombinant human antibody that specifically targets CD34. The specificity of this antibody for human CD34 has been confirmed through western blot analysis. Furthermore, it recognizes a class III epitope.
Figure 1 Characterization of anti-CD34 mouse mAbs.
Western blotting analysis of KG-1a cell membrane proteins with 2E10 is a commercial anti-CD34 mouse mAb.
Qian, W., Wang, L., Li, B., Wang, H., Hou, S., Hong, X., ... & Guo, Y. (2008). Development of new versions of anti-human CD34 monoclonal antibodies with potentially reduced immunogenicity. Biochemical and biophysical research communications, 367(2), 497-502.
Figure 2 Anti-CD34 mAbs recognized different epitopes on the CD34 molecule.
KG-1a cells were incubated for 30 min at 37 °C with neuraminidase. After washing twice with PBS containing 5% FCS, the enzyme-treated cells were incubated with 2E10 for 45 min at 4 °C. After washing, cells were labeled with FITC-conjugated goat anti-mouse IgG (H+L) and analyzed by FCM. The open histogram represents the staining of enzyme-treated cells and the filled histogram represents the staining of untreated cells.
Qian, W., Wang, L., Li, B., Wang, H., Hou, S., Hong, X., ... & Guo, Y. (2008). Development of new versions of anti-human CD34 monoclonal antibodies with potentially reduced immunogenicity. Biochemical and biophysical research communications, 367(2), 497-502.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-175-S(P) | Recombinant Anti-human CD34 Antibody scFv Fragment | ELISA, WB, IP, FuncS | scFv |
HPAB-M0472-YC-S(P) | Mouse Anti-CD34 Recombinant Antibody; scFv Fragment (HPAB-M0472-YC-S(P)) | WB, IF, IHC, IP, WB | Mouse scFv |
HPAB-M0473-YC-S(P) | Human Anti-CD34 Recombinant Antibody; scFv Fragment (HPAB-M0473-YC-S(P)) | ELISA | Mouse scFv |
HPAB-0883-WJ-S(P) | Mouse Anti-CD34 Recombinant Antibody; scFv Fragment (HPAB-0883-WJ-S(P)) | ELISA | Mouse scFv |
HPAB-0884-WJ-S(P) | Human Anti-CD34 Recombinant Antibody; scFv Fragment (HPAB-0884-WJ-S(P)) | ELISA | Humanized scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
MHH-175-F(E) | Recombinant Human Anti-human CD34 Antibody Fab Fragment | Neut, IF, FuncS | Fab |
HPAB-1042-FY-S(P) | Human Anti-CD34 Recombinant Antibody (clone c4C8); Fab Fragment | ELISA | Chimeric (mouse/human) Fab |
HPAB-1043-FY-S(P) | Human Anti-CD34 Recombinant Antibody (clone C5B12); Fab Fragment | ELISA | Chimeric (mouse/human) Fab |
HPAB-1044-FY-S(P) | Human Anti-CD34 Recombinant Antibody (clone C2e10); Fab Fragment | ELISA | Chimeric (mouse/human) Fab |
HPAB-0883-WJ-F(E) | Mouse Anti-CD34 Recombinant Antibody; Fab Fragment (HPAB-0883-WJ-F(E)) | ELISA | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-149LC | Anti-Human CD34 Recombinant Antibody (h4C8) | FC, Inhib | Humanized antibody |
TAB-149LC-S(P) | Anti-Human CD34 Recombinant Antibody scFv Fragment (h4C8) | ELISA | Humanized antibody |
TAB-149LC-F(E) | Anti-Human CD34 Recombinant Antibody Fab Fragment (h4C8) | ELISA | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-150LC | Human Anti-CD34 Recombinant Antibody (TAB-150LC) | ELISA | Human IgG |
TAB-150LC-S(P) | Human Anti-CD34 Recombinant Antibody; scFv Fragment (TAB-150LC-S(P)) | ELISA | Human scFv |
TAB-150LC-F(E) | Human Anti-CD34 Recombinant Antibody; Fab Fragment (TAB-150LC-F(E)) | ELISA | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-342CQ | Mouse Anti-CD34 Recombinant Antibody (clone 4H11) | Block, FC, IF | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-0554 | Hi-Affi™ Rabbit Anti-CD34 Recombinant Antibody (clone DS554AB) | IHC-P, IP, WB | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-1747-CN | Rabbit Anti-CD34 Polyclonal Antibody (MRO-1747-CN) | WB, IHC | Rabbit IgG |
MRO-1748-CN | Rabbit Anti-CD34 Polyclonal Antibody (MRO-1748-CN) | WB, IF, IHC, FC | Rabbit IgG |
HPAB-1042-FY | Human Anti-CD34 Recombinant Antibody (clone c4C8) | ELISA | Human IgG1, κ |
HPAB-1043-FY | Human Anti-CD34 Recombinant Antibody (clone C5B12) | FC | Human IgG2a, κ |
HPAB-1044-FY | Human Anti-CD34 Recombinant Antibody (clone C2e10) | ELISA | Human IgG3, κ |
There are currently no Customer reviews or questions for FAMAB-1049CQ. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.