This product is a recombinant mouse antibody that recognizes CD48. The antibody was purified by affinity chromatography. It can be used in Block, FC.
Figure 1 Effect of MRC OX-45 and MRC OX-46 MAbs on MLR proliferation.
HO lymph node cells were incubated with 5 x 105 irradiated F1 spleen cells for 4 days in RPMI medium containing 5% DA serum. The cells were cultured in 0.2 ml/well in sterile microtitre plates. Monoclonal antibodies were added to the culture at the beginning of the incubation as pure IgG and/or F(ab')2 for MRC OX-45 antibody. Cultures were labelled with 0.5 uCi [3H]thymidine 18 hr before the end of the incubation period, and the cells were harvested on glass fibre filters. Data are means and ranges of quadruplicate determinations. Cells were cultured with MRC OX-46 IgG (●) MRC OX-45F(ab')2 (○) or MRC OX-l IgG included as a control (△). The dose-response curve for MRC OX-45 IgG (not shown) was similar to those for MRC OX-46 IgG and MRC OX-45 F(ab')2.
Arvieux, J., Jefferies, W. A., Paterson, D. J., Williams, A. F., & Green, J. R. (1986). Monoclonal antibodies against a rat leucocyte antigen block antigen-induced T-cell responses via an effect on accessory cells. Immunology, 58(3), 337.
Figure 2 Time-course of IL-2 production in MLR in the presence of MRC OX-45 IgG.
Primary MLR between HO lymph node cells(2.5 x 105) and (HO x HO.B2) F, spleen cells (5 x 105) were incubated for 5 days in RPMI containing 5% DA serum with (●) or without (△)MRC OX-45 IgG added at the beginning of the culture. Supernatants were collected daily and IL-2 activity was assayed on Con A-activated blasts. One U/ml of IL-2 activity corresponded to the dilution that produced 10% maximal proliferation of target cells.
Arvieux, J., Jefferies, W. A., Paterson, D. J., Williams, A. F., & Green, J. R. (1986). Monoclonal antibodies against a rat leucocyte antigen block antigen-induced T-cell responses via an effect on accessory cells. Immunology, 58(3), 337.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
TAB-132CL | Anti-Human CD48 Recombinant Antibody | ELISA, Inhib, FuncS | Antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-307LC | Mouse Anti-CD48 Recombinant Antibody (TAB-307LC) | ELISA, Cyt, CDC | Mouse IgG2a |
TAB-307LC-S(P) | Mouse Anti-CD48 Recombinant Antibody; scFv Fragment (TAB-307LC-S(P)) | ELISA | Mouse scFv |
TAB-307LC-F(E) | Mouse Anti-CD48 Recombinant Antibody; Fab Fragment (TAB-307LC-F(E)) | ELISA | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-304LC-S(P) | Human Anti-CD48 Recombinant Antibody (TAB-304LC-S(P)); scFv Fragment | ELISA | Human scFv |
TAB-305LC-S(P) | Mouse Anti-CD48 Recombinant Antibody (TAB-305LC-S(P)); scFv Fragment | ELISA | Mouse scFv |
TAB-306LC-S(P) | Human Anti-CD48 Recombinant Antibody (TAB-306LC-S(P)); scFv Fragment | ELISA | Human scFv |
TAB-304LC-F(E) | Human Anti-CD48 Recombinant Antibody (TAB-304LC-F(E)); Fab Fragment | ELISA | Human Fab |
TAB-305LC-F(E) | Mouse Anti-CD48 Recombinant Antibody (TAB-305LC-F(E)); Fab Fragment | ELISA | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-390CQ | Hamster Anti-CD48 Recombinant Antibody (clone HM48-1) | FC, IP, Costim, Block | Hamster IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-0566 | Hi-Affi™ Rabbit Anti-CD48 Recombinant Antibody (clone DS566AB) | WB, IHC, ICC, IP | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-1325LY-S(P) | Human Anti-CD48 Recombinant Antibody; scFv Fragment (HPAB-1325LY-S(P)) | ELISA | Human scfv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-1325LY-F(E) | Human Anti-CD48 Recombinant Antibody; Fab Fragment (HPAB-1325LY-F(E)) | ELISA | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
FN-192CQ | Mouse Anti-CD48 Recombinant Antibody (clone 156-4H9) | Neut, FuncS, FC | Mouse IgG1 |
ZG-0260U | Mouse Anti-CD48 Recombinant Antibody (clone 6F9H2) | ELISA, WB, IF, FC | Mouse IgG1 |
ZG-0261U | Mouse Anti-CD48 Recombinant Antibody (clone 26C2C11) | ELISA, WB, IF, FC | Mouse IgG1 |
VS3-XY357 | Mouse Anti-CD48 Recombinant Antibody, FITC (clone 4A156-4H9) | FC, IF | Mouse IgG1 |
VS3-XY358 | Mouse Anti-CD48 Recombinant Antibody, PE (clone 4A156-4H9) | FC, IF | Mouse IgG1 |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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