This product is a recombinant antibody that recognizes CD79b. The monoclonal antibody MA79b reacts with the epitope of CD79b.
Figure 1 Shows a graph of inhibition of in vivo tumor growth in a BJAB-luciferase xenograft mode.
Administration of anti-CD79b antibodies/chMA79b-SMCC-DM1, drug load was approximately 2.9 and huMA79b L2/H3-SMCC-DM1, drug load was approximately 2.4 to SCID mice having human B cell tumors significantly inhibited tumor growth.
Figure 2 Shows a graph of inhibition of in vivo tumor growth in a Granta-519 (Human Mantle Cell Lymphoma) xenograft model.
Administration of anti-CD79b antibodies/chMA79b-SMCC-DM1, drug load was approximately 3.6 and huMA79b.v17-SMCC-DM1, drug load was approximately 3.4 to SCID mice having human B cell tumors significantly inhibited tumor growth.
Figure 3 Shows FACS plots indicating that binding of anti-CD79b thioMAb drug conjugates (TDCs) of the invention bind to CD79b expressed on the surface of BJAB-luciferase cells is similar for conjugated LC (V205C) thioMAb variants.
Figure 4 Shows FACS plots indicating that binding of anti-CD79b thioMAb drug conjugates (TDCs) of the invention bind to CD79b expressed on the surface of BJAB-luciferase cells is similar for naked (unconjugated) HC (A118C) thioMAb variants of huMA79b.v18.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1219z | Mouse Anti-CD79B Recombinant Antibody (clone 32B11) | ELISA, WB, FC, FuncS | Mouse IgG1 |
HPAB-0364LY | Human Anti-CD79B Recombinant Antibody (HPAB-0364LY) | Inhib, ELISA | Human IgG |
FN-062CQ | Mouse Anti-CD79B Recombinant Antibody (clone SN8) | FC, FuncS, WB | Mouse IgG1, κ |
HPAB-J0057-YC | Human Anti-CD79B Recombinant Antibody (HPAB-J0057-YC) | ELISA, FC, Inhib, FuncS | Humanized IgG1 |
HPAB-1939-FY | Human Anti-CD79B Recombinant Antibody (clone huMA79b) | FuncS, Inhib | Humanized IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-897 | Humanized Anti-CD79B Recombinant Antibody (clone Polatuzumab) | Neut, ELISA, IF, IP, FuncS, FC, ICC | Humanized (from mouse) IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-0581 | Hi-Affi™ Rabbit Anti-CD79B Recombinant Antibody (clone DS581AB) | WB, IHC, ICC, IP, FC | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-LC1918 | PE-A*02:01/Human CD79B (LLSAEPVPA) MHC Tetramer | FCM |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0058-YC-S(P) | Hamster Anti-Cd79b Recombinant Antibody (clone HM79-16); scFv Fragment | FuncS | Hamster scFv |
HPAB-618-FY-S(P) | Human Anti-CD79B Recombinant Antibody; scFv Fragment (HPAB-618-FY-S(P)) | FC, ELISA | Humanized scFv |
HPAB-619-FY-S(P) | Human Anti-CD79B Recombinant Antibody; scFv Fragment (HPAB-619-FY-S(P)) | FC, ELISA | Humanized scFv |
HPAB-N0044-YC-S(P) | Human Anti-CD79b Recombinant Antibody; scFv Fragment (HPAB-N0044-YC-S(P)) | FuncS | Humanized scFv |
HPAB-1491-FY-F(E) | Human Anti-CD79B Recombinant Antibody (clone P2C2); scFv Fragment | ELISA, WB | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0364LY-F(E) | Human Anti-CD79B Recombinant Antibody; Fab Fragment (HPAB-0364LY-F(E)) | Inhib, ELISA | Human Fab |
HPAB-J0055-YC-F(E) | Human Anti-CD79B Recombinant Antibody; Fab Fragment (HPAB-J0055-YC-F(E)) | ELISA, FC, Inhib, FuncS | Humanized Fab |
HPAB-J0056-YC-F(E) | Human Anti-CD79B Recombinant Antibody; Fab Fragment (HPAB-J0056-YC-F(E)) | ELISA, FC, Inhib, FuncS | Humanized Fab |
HPAB-J0057-YC-F(E) | Human Anti-CD79B Recombinant Antibody; Fab Fragment (HPAB-J0057-YC-F(E)) | ELISA, FC, Inhib, FuncS | Humanized Fab |
HPAB-1938-FY-F(E) | Mouse Anti-CD79B Recombinant Antibody (clone MA79b); Fab Fragment | ELISA, FC, FuncS | Mouse Fab, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-897 | Afuco™ Anti-CD79B ADCC Recombinant Antibody (Polatuzumab), ADCC Enhanced | Neut, ELISA, IF, IP, FuncS, FC | ADCC enhanced antibody |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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