Rabbit Anti-CFD Recombinant Antibody (clone R09-6A9) (CAT#: VS3-FY1712)

This anti-Factor D antibody detected positive in western blot analysis of factor D in Hela lysates. The recombinant monoclonal antibody is used to detect human CFD. Western blot demonstrated that CFD antibody recognized a target protein with a molecular weight of 27 kDa.


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WB

Figure 1 Anti-CFD Antibody (VS3-FY1712) in WB.

Figure 1 Anti-CFD Antibody (VS3-FY1712) in WB.

The Factor D expression in Hela lysates were detected using the anti-Factor D by western blot assay.


Specifications

  • Immunogen
  • Recombinant human factor D protein
  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human CFD
  • Species Reactivity
  • Human
  • Clone
  • R09-6A9
  • Applications
  • Western Blot
  • MW
  • The calculated weight of the target protein is approximately 27 kDa, while the observed molecular weight stands at 27 kDa.
  • Related Disease
  • Age-related macular degeneration (AMD); including dry and wet (non-exudative and exudative) forms; choroidal neovascularization (CNV); uveitis; diabetic and other ischemia-related retinopathies; endophthalmitis; and other intraocular neovascular diseases

Product Property

  • Purification
  • Affinity Purified
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • Western Blot: 1/500-1/1000

Target

  • Alternative Names
  • Complement Factor D; Properdin Factor D; Adipsin; D Component Of Complement (Adipsin); C3 Convertase Activator; EC 3.4.21.46; PFD
  • Sequence Similarities
  • Belongs to the peptidase S1 family.
  • Cellular Localization
  • Secreted
  • Post Translation Modifications
  • Disulfide bond
    Zymogen
  • Function
  • Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.

Recommended Products

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

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Humanized Antibody

CAT Product Name Application Type
TAB-754 Anti-CFD Recombinant Antibody (Lampalizumab) ELISA, IP, FC, FuncS, Neut, IF Fab - G1 - kappa

Single-domain Antibody

CAT Product Name Application Type
PNBL-034 Recombinant Anti-CHRM2 VHH Single Domain Antibody (PNBL-034) FACS Llama VHH

Rabbit Monoclonal Antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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