Mouse Anti-CR1 Recombinant Antibody (clone 8C12) (CAT#: FAMAB-1102CQ)

This product is a recombinant mouse antibody that recognizes CR1. The antibody was purified by affinity chromatography. It can be used in IP, WB, FC, IHC-Fr.


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FC

Figure 1 Lower CR1 expression and fewer CR1+B cells after ovariectomy in WT mice.

Figure 1 Lower CR1 expression and fewer CR1+B cells after ovariectomy in WT mice.

Representative dot plots showing splenocytes from OE and sham-operated female WT mice stained with anti-B220-PE, anti-CR1-biotin, and streptavidin-FITC.

Nilsson, K. E., Andrén, M., De Ståhl, T. D., & Kleinau, S. (2009). Enhanced susceptibility to low‐dose collagen‐induced arthritis in CR1/2‐deficient female mice—possible role of estrogen on CR1 expression. The FASEB Journal, 23(8), 2450-2458.

FC

Figure 2 Splenic B220+B cells were further separated into FO B cells and MZB cells, according to their cell-specific markers.

Figure 2 Splenic B220+B cells were further separated into FO B cells and MZB cells, according to their cell-specific markers.

Representative histograms showing CR1 expressionin FO from OE (solid) and sham-operated (shaded) WT female mice using anti-CR1-biotin and streptavidin-APC.

Nilsson, K. E., Andrén, M., De Ståhl, T. D., & Kleinau, S. (2009). Enhanced susceptibility to low‐dose collagen‐induced arthritis in CR1/2‐deficient female mice—possible role of estrogen on CR1 expression. The FASEB Journal, 23(8), 2450-2458.


Specifications

  • Immunogen
  • Purified murine CR1 protein
  • Host Species
  • Mouse
  • Type
  • Mouse IgG1
  • Species Reactivity
  • Mouse
  • Clone
  • 8C12
  • Applications
  • FC

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • This antibody has been reported for use in Flow Cytometry.

Target

  • Alternative Names
  • Complement C3b/C4b Receptor 1 (Knops Blood Group); Complement Component (3b/4b) Receptor 1 (Knops Blood Group); C3b/C4b Receptor; CD35 Antigen; C3BR; Complement Component (3b/4b) Receptor 1, Including Knops Blood Group System; Complement Component 3b/4b Receptor 1 (Knops Blood Group)

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "CR1"

Blocking Antibody

CAT Product Name Application Type
NEUT-496CQ Mouse Anti-CR1 Recombinant Antibody (clone J3D3) Block, ELISA, FC, IHC-Fr, IHC-P Mouse IgG1, κ

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-0794 Hi-Affi™ Rabbit Anti-CR1 Recombinant Antibody (clone DS794AB) WB, IHC Rabbit IgG

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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