Rabbit Anti-CSF1 Recombinant Antibody (VS3-CJ542) (CAT#: VS3-CJ542)
This product is a rabbit antibody that recognizes human CSF1.
Specific Inquiry
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/76624/1709_G12_12_cr5800dfbe06bb5_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/76624/1709_G12_12_cr5800dfbe06bb5_selected.jpg
Figure 2 IF staining of human cell line ASC TERT1
(Immunofluorescent staining of human cell line ASC TERT1 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/76624/1876_A10_31_blue_red_green.jpg
(Immunofluorescent staining of human cell line ASC TERT1 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/76624/1876_A10_31_blue_red_green.jpg
Figure 3 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nuclear bodies.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/76624/1769_A4_33_blue_red_green.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to nuclear bodies.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/76624/1769_A4_33_blue_red_green.jpg
Figure 4 RNA cell line category: Cell line enhanced (ASC diff, BJ hTERT+, GAMG, HHSteC, HSkMC, hTERT-RPE1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000184371-CSF1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000184371-CSF1
Specifications
- Immunogen
- Recombinant protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human CSF1
- Species Reactivity
- Human
- Applications
- WB, ICC, IHC, IP
- Conjugate
- Unconjugated
Product Property
- Purification
- Protein A affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- 40% Glycerol, 1% BSA, TBS, pH7.4.
- Preservative
- 0.05% Sodium Azide
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Western Blot, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation.
Target
- Alternative Names
- MCSF; CSF-1
- Gene ID
- 1435
- UniProt ID
- P09603
- Cellular Localization
- Cell membrane, Membrane, Secreted
- Post Translation Modifications
- N- and O-glycosylated. Glycosylation and proteolytic cleavage yield different soluble forms. One high molecular weight soluble form is a proteoglycan containing chondroitin sulfate. O-glycosylated with core 1 or possibly core 8 glycans. Isoform 1 is N- and O-glycosylated. Isoform 3 is only N-glycosylated.
- Protein Refseq
- NP_000748.3; NP_757349.1; NP_757350.1
- Function
- Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of pro-inflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance.
Recommended Products
Isotype Control
Secondary Antibody
Related Resources
TNF Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "CSF1"
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-245-S(P) | Recombinant Anti-human CSF1 Antibody scFv Fragment | ELISA, IP, FuncS | scFv |
| HPAB-0110-WJ-S(P) | Human Anti-CSF1 Recombinant Antibody; scFv Fragment (HPAB-0110-WJ-S(P)) | ELISA, FC, WB | Human scFv |
| HPAB-0748-WJ-S(P) | Human Anti-CSF1 Recombinant Antibody (clone 88); scFv Fragment | ELISA, WB, FC | Human scFv |
| HPAB-0749-WJ-S(P) | Human Anti-CSF1 Recombinant Antibody (clone 100); scFv Fragment | ELISA, WB, FC | Human scFv |
| HPAB-0750-WJ-S(P) | Human Anti-CSF1 Recombinant Antibody (clone 3.8.3); scFv Fragment | ELISA, WB, FC | Human scFv |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-187CL | Human Anti-CSF1 Recombinant Antibody (TAB-187CL) | ELISA | Human IgG |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-501CQ | Mouse Anti-CSF1 Recombinant Antibody (clone 3V17) | Neut, WB | Mouse IgG2 |
| NEUT-502CQ | Mouse Anti-CSF1 Recombinant Antibody (clone CBL140) | Neut, WB | Mouse IgG2 |
| NEUT-503CQ | Mouse Anti-CSF1 Recombinant Antibody (clone CBL441) | WB, Neut | Mouse IgG2a |
| NEUT-505CQ | Rat Anti-Csf1 Recombinant Antibody (clone CBL205) | WB, Neut | Rat IgG2 |
| NEUT-506CQ | Rat Anti-Csf1 Recombinant Antibody (clone CBL535) | WB, Neut | Rat IgG2b |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-504CQ | Rat Anti-Csf1 Recombinant Antibody (clone 5A1) | Block | Rat IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0824 | Hi-Affi™ Rabbit Anti-CSF1 Recombinant Antibody (clone DS824AB) | ICC, IHC-P, IP, WB | Rabbit IgG |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-029ML | Anti-Human CSF1 Recombinant Antibody (Lacnotuzumab) | ELISA, IHC, FC, IP, IF, FuncS | IgG1, κ |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0532-CN | Mouse Anti-CSF1 Recombinant Antibody (HPAB-0532-CN) | ELISA, FC, Neut | Mouse IgG |
| HPAB-0533-CN | Mouse Anti-CSF1 Recombinant Antibody (HPAB-0533-CN) | ELISA, FC, Neut | Mouse IgG |
| HPAB-0534-CN | Mouse Anti-CSF1 Recombinant Antibody (HPAB-0534-CN) | ELISA, FC, Neut | Mouse IgG |
| HPAB-0535-CN | Human Anti-CSF1 Recombinant Antibody (HPAB-0535-CN) | ELISA, FC, Neut | Humanized IgG1 |
| HPAB-0537-CN | Human Anti-CSF1 Recombinant Antibody (HPAB-0537-CN) | ELISA, FC | Human IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0532-CN-F(E) | Mouse Anti-CSF1 Recombinant Antibody; Fab Fragment (HPAB-0532-CN-F(E)) | ELISA, FC, Neut | Mouse Fab |
| HPAB-0533-CN-F(E) | Mouse Anti-CSF1 Recombinant Antibody; Fab Fragment (HPAB-0533-CN-F(E)) | ELISA, FC, Neut | Mouse Fab |
| HPAB-0534-CN-F(E) | Mouse Anti-CSF1 Recombinant Antibody; Fab Fragment (HPAB-0534-CN-F(E)) | ELISA, FC, Neut | Mouse Fab |
| HPAB-0535-CN-F(E) | Human Anti-CSF1 Recombinant Antibody; Fab Fragment (HPAB-0535-CN-F(E)) | ELISA, FC, Neut | Humanized Fab |
| HPAB-0537-CN-F(E) | Human Anti-CSF1 Recombinant Antibody; Fab Fragment (HPAB-0537-CN-F(E)) | ELISA, FC | Human Fab |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-029ML | Afuco™ Anti-CSF1 ADCC Recombinant Antibody (Lacnotuzumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, FuncS | ADCC enhanced antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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