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  • Mouse Anti-CTNND1 Recombinant Antibody (VS3-CJ159)

Mouse Anti-CTNND1 Recombinant Antibody (VS3-CJ159) (CAT#: VS3-CJ159)

This product is a mouse antibody that recognizes CTNND1.


See more Engineered Antibody products for CTNND1
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  • Gene Expression
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Subcellular Location
Figure 1 IF staining of human cell line A-431
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15955/if_selected.jpg
Figure 2 IF staining of human cell line U-251 MG
Figure 2 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3837/if_selected.jpg
Normal Tissue
Figure 3 Small intestine
Figure 3 Small intestine
(High expression in small intestine)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15954/ihc_selected.jpg
Figure 4 IHC staining of human small intestine
Figure 4 IHC staining of human small intestine
(Immunohistochemical staining of human small intestine shows cytoplasmic and membranous positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15955/36069_A_6_2_selected.jpg
Figure 5 Liver
Figure 5 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15955/36069_A_7_4.jpg
Figure 6 Lymph node
Figure 6 Lymph node
(Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15955/36069_A_9_8.jpg
Figure 7 Colon
Figure 7 Colon
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/15955/36069_A_7_3.jpg
RNA Expression
Figure 8 RNA cell line category: Low cell line specificity
Figure 8 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000198561-CTNND1

Specifications

  • Immunogen
  • KLH-conjugated synthetic peptide encompassing a sequence within human Catenin delta 1
  • Host Species
  • Mouse
  • Type
  • Mouse IgG
  • Specificity
  • Human CTNND1
  • Species Reactivity
  • Human
  • Applications
  • WB, IHC
  • Conjugate
  • Unconjugated

Product Property

  • Purification
  • Immunogen affinity chromatography
  • Purity
  • >95% as determined by SDS-PAGE
  • Format
  • Liquid
  • Buffer
  • 50% Glycerol, 0.2% BSA, PBS.
  • Preservative
  • 0.02% sodium azide
  • Storage
  • Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
  • Shipping
  • Ice packs

Applications

  • Application Notes
  • This antibody has been tested for use in Western Blot (1:500-1:1000), Immunohistochemistry (1:100-1:300).

Target

  • Alternative Names
  • CAS; p120; BCDS2; CTNND; P120CAS; P120CTN; p120(CAS); p120(CTN)
  • Sequence Similarities
  • Belongs to the beta-catenin family.
  • Cellular Localization
  • Cell junction, Cell membrane, Cytoplasm, Membrane, Nucleus
  • Post Translation Modifications
  • Phosphorylated by FER and other protein-tyrosine kinases. Phosphorylated at Ser-288 by PAK5. Dephosphorylated by PTPRJ.
  • Function
  • Key regulator of cell-cell adhesion that associates with and regulates the cell adhesion properties of both C-, E- and N-cadherins, being critical for their surface stability (PubMed:14610055, PubMed:20371349).
    Beside cell-cell adhesion, regulates gene transcription through several transcription factors including ZBTB33/Kaiso2 and GLIS2, and the activity of Rho family GTPases and downstream cytoskeletal dynamics (PubMed:10207085, PubMed:20371349).
    Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors (PubMed:17344476).

Recommended Products

Isotype Control

Secondary Antibody

Recommended Dilution Buffer

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "CTNND1"

Recombinant Antibody

CAT Product Name Application Type
MOB-3971z Mouse Anti-CTNND1 Recombinant Antibody (clone 43H7) WB, IP, IF Mouse IgG1, κ
MOB-0047CT Recombinant Mouse anti-Human CTNND1 Monoclonal antibody (3345D7b) Dot, ICC, WB

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-0862 Hi-Affi™ Rabbit Anti-CTNND1 Recombinant Antibody (clone DS862AB) ICC, IF, IHC-P, WB Rabbit IgG

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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