Mouse Anti-CXCL8 Recombinant Antibody (clone 5.12.14); Fab Fragment (CAT#: HPAB-0664-YJ-F(E))
This product is a recombinant mouse antibody Fab fragment that recognizes human CXCL8. It may be used therapeutically in the treatment of other inflammatory disorders, such as bacterial pneumonias and inflammatory bowel disease.
Specific Inquiry
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57179/1010_F11_1_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57179/1010_F11_1_selected.jpg
Figure 2 IHC staining of human lymph node
(Immunohistochemical staining of human lymph node shows moderate cytoplasmic positivity in non germinal center cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57179/ihc_selected.jpg
(Immunohistochemical staining of human lymph node shows moderate cytoplasmic positivity in non germinal center cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57179/ihc_selected.jpg
Figure 3 IF staining of human cell line GAMG
(Immunofluorescent staining of human cell line GAMG shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57179/2058_E8_1_blue_red_green.jpg
(Immunofluorescent staining of human cell line GAMG shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57179/2058_E8_1_blue_red_green.jpg
Figure 4 Kidney
(Cells in tubules
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57179/131156_A_7_5.jpg
(Cells in tubules
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57179/131156_A_7_5.jpg
Figure 5 Testis
(Sertoli cells
Staining:Medium
Intensity: Moderate
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57179/131156_A_6_6.jpg
(Sertoli cells
Staining:Medium
Intensity: Moderate
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57179/131156_A_6_6.jpg
Figure 6 Lymph node
(Non-germinal center cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57179/131156_A_8_8.jpg
(Non-germinal center cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57179/131156_A_8_8.jpg
Figure 7 RNA cell line category: Group enriched (BJ hTERT+, GAMG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169429-CXCL8
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169429-CXCL8
Specifications
- Immunogen
- Recombinant human IL-8 (produced as a fusion of (ser-IL-8)72 with ubiquitin.
- Host Species
- Mouse
- Type
- Mouse Fab
- Specificity
- Human CXCL8
- Species Reactivity
- Human
- Clone
- 5.12.14
- Applications
- ELISA, WB, Inhib, Antagonist
- Related Disease
- Inflammatory disorders
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- IL8; NAF; GCP1; LECT; LUCT; NAP1; GCP-1; LYNAP; MDNCF; MONAP; NAP-1; interleukin-8; T-cell chemotactic factor; alveolar macrophage chemotactic factor I; beta endothelial cell-derived neutrophil activating peptide; beta-thromboglobulin-like protein; chemokine (C-X-C motif) ligand 8; emoctakin; granulocyte chemotactic protein 1; interleukin 8; lung giant cell carcinoma-derived chemotactic protein; lymphocyte derived neutrophil activating peptide; monocyte-derived neutrophil chemotactic factor; monocyte-derived neutrophil-activating peptide; neutrophil-activating peptide 1; small inducible cytokine subfamily B, member 8; tumor necrosis factor-induced gene 1
- Gene ID
- 3576
- UniProt ID
- P10145
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone 5.12.14"
See other products for "CXCL8"
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-738-sdAb | Recombinant Anti-human CXCL8 VHH Single Domain Antibody | IHC, ICC, FC, FA, FUNC | Llama VHH |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-201CL | Human Anti-CXCL8 Recombinant Antibody (TAB-201CL) | ELISA | Human IgG2 |
| TAB-701LC | Human Anti-CXCL8 Recombinant Antibody (TAB-701LC) | ELISA, FC, FuncS | Human IgG1, κ |
| TAB-701LC-S(P) | Human Anti-CXCL8 Recombinant Antibody; scFv Fragment (TAB-701LC-S(P)) | ELISA | Human scFv |
| TAB-701LC-F(E) | Human Anti-CXCL8 Recombinant Antibody; Fab Fragment (TAB-701LC-F(E)) | ELISA | Human Fab |
Fc Glycosylation
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-095LC | Recombinant Anti-Human CXCL8 Antibody (Fc glycosylation) | ELISA | Humanized antibody |
Deglycosylated Antibody (Non-glycosylated IgGs)
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-164LC | Recombinant Anti-Human CXCL8 Antibody (Non-glycosylated) | ELISA | Mouse antibody |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-644CQ | Mouse Anti-CXCL8 Recombinant Antibody (clone CBL601) | ELISA, Neut | Mouse IgG1 |
| NEUT-645CQ | Mouse Anti-CXCL8 Recombinant Antibody (clone CBL602) | WB, ICC, Neut | Mouse IgG1 |
| NEUT-646CQ | Mouse Anti-CXCL8 Recombinant Antibody (clone CBL115) | FC, WB, IHC, Neut | Mouse IgG1 |
| NEUT-647CQ | Mouse Anti-CXCL8 Recombinant Antibody (clone I8-60) | ELISA, Neut, WB | Mouse IgG1, κ |
| NEUT-648CQ | Mouse Anti-CXCL8 Recombinant Antibody (clone I8-S2) | ELISA, Neut, WB | Mouse IgG2b, κ |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-660CQ | Mouse Anti-CXCL8 Recombinant Antibody (clone B-K8) | Block, ICFC | Mouse IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4128 | Hi-Affi™ Rabbit Anti-CXCL8 Recombinant Antibody (clone SI199DS) | ELISA | Rabbit IgG |
| MOR-4624 | Hi-Affi™ Rabbit Anti-CXCL8 Recombinant Antibody (clone TH137DS) | WB | Rabbit IgG |
| MOR-4625 | Hi-Affi™ Rabbit Anti-CXCL8 Recombinant Antibody (clone TH138DS) | WB | Rabbit IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0059-YC | Human Anti-CXCL8 Recombinant Antibody (HPAB-N0059-YC) | FuncS | Human IgG |
| HPAB-A1375-YJ | Human Anti-CXCL8 Recombinant Antibody (clone K4.2) | ELISA, SPR | Human lgG2 |
| HPAB-A1376-YJ | Human Anti-CXCL8 Recombinant Antibody (clone D1.1) | ELISA, SPR | Human lgG2 |
| HPAB-A1377-YJ | Human Anti-CXCL8 Recombinant Antibody (clone K2.2) | ELISA, Inhib, Neut, FuncS, SPR | Human lgG2 |
| HPAB-A1378-YJ | Human Anti-CXCL8 Recombinant Antibody (clone K4.3) | ELISA, Inhib, Neut, FuncS, SPR | Human lgG2 |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0059-YC-S(P) | Human Anti-CXCL8 Recombinant Antibody; scFv Fragment (HPAB-N0059-YC-S(P)) | FuncS | Human scFv |
| HPAB-1101-FY-F(E) | Mouse Anti-CXCL8 Recombinant Antibody (clone 656.35); scFv Fragment | ELISA, IA, Block | Mouse scFv |
| HPAB-1102-FY-F(E) | Mouse Anti-CXCL8 Recombinant Antibody (clone 197.2); scFv Fragment | ELISA, IA, Block | Mouse scFv |
| HPAB-1103-FY-F(E) | Mouse Anti-CXCL8 Recombinant Antibody (clone 81.1); scFv Fragment | ELISA, IA, Block | Mouse scFv |
| HPAB-1544WJ-S(P) | Human Anti-CXCL8 Recombinant Antibody; scFv Fragment (clone K2.2.1) | ELISA, WB | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0665-YJ-F(E) | Human Anti-CXCL8 Recombinant Antibody (clone ch5.12.14); Fab Fragment | ELISA, WB, Inhib, Antagonist | Chimeric (mouse/human) Fab |
| HPAB-1841-FY-S(P) | Human Anti-CXCL8 Recombinant Antibody (clone WS-4); Fab Fragment | Inhib | Humanized Fab |
| HPAB-S0084-YC-F(E) | Mouse Anti-CXCL8 Recombinant Antibody (clone 6G4.2.5); Fab Fragment | ELISA, Inhib | Mouse Fab |
| HPAB-S0085-YC-F(E) | Human Anti-CXCL8 Recombinant Antibody (clone ch6G4.2.5); Fab Fragment | ELISA, Inhib | Chimeric (mouse/human) Fab |
| HPAB-S0086-YC-F(E) | Human Anti-CXCL8 Recombinant Antibody (clone h6G4V11); Fab Fragment | ELISA, Inhib | Humanized Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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