Human Anti-D3H44 Recombinant Antibody (clone 6A6) (CAT#: FAMAB-1718CQ)
This product is a recombinant human antibody that recognizes D3H44. The antibody was purified by affinity chromatography. It can be used in ELISA.
Specific Inquiry
Figure 1 Neutralization of D3H44 by 6A6 in TF/F.VIIa-mediated activation of F.X.
10 nM D3H44 (F(ab')2, Fab or IgG4b) was incubated with mTF1-263, F.VIIa(0.02 nM) and increasing concentrations of 6A6 antibody for 25 minutes in HBSA buffer. F.X (200 nM) was added and at various time-points reaction aliquots were with-drawn and analyzed for F.Xa in a second stage chromogenic substrate assay. The linear rates of initial of F.Xa formation were determined and are expressed as fractional activities. Open circles, D3H44-F(ab')2; triangles, D3H44-IgG4b; filled circles, D3H44-Fab;squares, 5G6 antibody.
Eigenbrot, C., Meng, Y. G., Krishnamurthy, R., Lipari, M. T., Presta, L., Devaux, B., ... & Kirchhofer, D. (2003). Structural insight into how an anti-idiotypic antibody against D3H44 (anti-tissue factor antibody) restores normal coagulation. Journal of molecular biology, 331(2), 433-446.
Figure 2 Binding of anti-TF antibodies to 6A6 antibody coated on the ELISA plate.
Eigenbrot, C., Meng, Y. G., Krishnamurthy, R., Lipari, M. T., Presta, L., Devaux, B., ... & Kirchhofer, D. (2003). Structural insight into how an anti-idiotypic antibody against D3H44 (anti-tissue factor antibody) restores normal coagulation. Journal of molecular biology, 331(2), 433-446.
Specifications
- Immunogen
- Humanised monoclonal antibody D3H44
- Host Species
- Human
- Type
- Human IgG1
- Species Reactivity
- Human
- Clone
- 6A6
- Applications
- ELISA
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- D3H44
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "D3H44"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-265 | Recombinant Anti-human D3H44 Antibody | WB, IHC, FuncS | IgG |
| MHH-265 | Recombinant Human Anti-human D3H44 Antibody | WB, FACS, FuncS | IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-265-F(E) | Recombinant Anti-human D3H44 Antibody Fab Fragment | RIA, IF, FuncS | Fab |
| MHH-265-F(E) | Recombinant Human Anti-human D3H44 Antibody Fab Fragment | IF, FC, Biosensors, FuncS | Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-265-S(P) | Recombinant Anti-human D3H44 Antibody scFv Fragment | ELISA, IF, FuncS | scFv |
| MHH-265-S(P) | Recombinant Human Anti-human D3H44 Antibody scFv Fragment | WB, Neut, FuncS | scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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