Rabbit Anti-DKK3 Recombinant Antibody (clone R03-8G7) (CAT#: VS3-FY1698)
This anti-DKK3 antibody detected in western blot analysis of Dkk3 in rat brain lysates. This clone R03-8G7 is a rabbit recombinant monoclonal antibody that is created to detect human and rat DKK3. It is suitable for use in a variety of assays, including WB, IP.
Specific Inquiry
WB
Figure 1 Anti-DKK3 Antibody (VS3-FY1698) in WB.
The Dkk3 expression in rat Brain lysates were detected using the anti-DKK3 by western blot assay.
Specifications
- Immunogen
- Recombinant human Dkk3 protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human and Rat DKK3
- Species Reactivity
- Human, Rat
- Clone
- R03-8G7
- Applications
- Western Blot, Immunoprecipitation
- MW
- The calculated weight of the target protein is approximately 38 kDa, while the observed molecular weight stands at 70 kDa.
- Related Disease
- Cancer
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunoprecipitation: 1/20
Target
- Alternative Names
- Dickkopf WNT Signaling Pathway Inhibitor 3; Regulated In Glioma; Dickkopf-3; HDkk-3; Dkk-3; REIC; Dickkopf (Xenopus Laevis) Homolog 3; Dickkopf 3 Homolog (Xenopus Laevis)
- Gene ID
- 27122
- UniProt ID
- Q9UBP4
- Sequence Similarities
- Belongs to the dickkopf family.
- Cellular Localization
- Secreted
- Post Translation Modifications
- N- and O-glycosylated.
- Protein Refseq
- XP_006718241.1; XP_016873044.1; XP_047282730.1; XP_047282731.1; NP_001018067.1
- Function
- Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).
Recommended Products
Isotype Control
Secondary Antibody
Related Resources
Canonical Wnt Signaling Pathway
Non-Canonical Wnt Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "DKK3"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0055CT | Recombinant Mouse anti-Human DKK3 Monoclonal antibody (5H8) | ELISA, FC, WB | |
| HPAB-2833LY | Mouse Anti-DKK3 Recombinant Antibody (HPAB-2833LY) | ELISA, FC, Block | Mouse IgG |
| VS3-QX326 | Mouse Anti-DKK3 Recombinant Antibody (clone 4G7) | WB, IHC, ICC, FC, ELISA | Mouse IgG1 |
| VS3-XY580 | Mouse Anti-DKK3 Recombinant Antibody (clone 8A5C6) | ELISA, WB, IHC, FC | Mouse IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4138 | Hi-Affi™ Rabbit Anti-Dkk3 Recombinant Antibody (clone SI211DS) | ELISA | Rabbit IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2833LY-S(P) | Mouse Anti-DKK3 Recombinant Antibody; scFv Fragment (HPAB-2833LY-S(P)) | ELISA, FC, Block | Mouse scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2833LY-F(E) | Mouse Anti-DKK3 Recombinant Antibody; Fab Fragment (HPAB-2833LY-F(E)) | ELISA, FC, Block | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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