Rabbit Anti-DSG1 Recombinant Antibody (clone R07-2K4) (CAT#: VS3-XY3338)
This product is a recombinant rabbit antibody that recognizes DSG1 (Desmoglein 1), which is a component of intercellular desmosome junctions. It has been used in a variety of applications, such as Western Blot, Immunohistochemistry-Paraffin, Immunocytochemistry or Immunofluorescence. The recommended dilutions of Western Blot, Immunohistochemistry-Paraffin and Immunofluorescence is 1/500-1/1000, 1/50-1/100 and 1/50-1/200, respectively.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Skin
(Cells in basal layer
Staining:Medium
Intensity: Moderate
Quantity:>75%
Cells in corneal layer
Staining:High
Intensity: Strong
Quantity: 75%-25%
Cells in granular layer
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Cells in spinous layer
Staining:High
Intensity: Strong
Quantity:>75%
Langerhans cells
Staining:High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/22128/169913_B_8_1.jpg
(Cells in basal layer
Staining:Medium
Intensity: Moderate
Quantity:>75%
Cells in corneal layer
Staining:High
Intensity: Strong
Quantity: 75%-25%
Cells in granular layer
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Cells in spinous layer
Staining:High
Intensity: Strong
Quantity:>75%
Langerhans cells
Staining:High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/22128/169913_B_8_1.jpg
Figure 2 RNA cell line category: Cell line enriched (hTCEpi)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000134760-DSG1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000134760-DSG1
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat DSG1
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R07-2K4
- Applications
- WB, IHC-P, ICC, IF
- Related Disease
- Erythroderma
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IHC: 1/50-1/100
IF: 1/50-1/200
Target
- Alternative Names
- DG1; DSG; CDHF4; EPKHE; PPKS1; SPPK1; EPKHIA
- Gene ID
- 1828
- UniProt ID
- Q02413
- Long Name
- Desmoglein 1
- Cellular Localization
- Cell membrane, Cell junction, Cytoplasm, Nucleus
- Post Translation Modifications
- Glycosylation at Asn36, Asn110, and Asn180 (NX_Q02413 [NX_Q02413-1])
Modification sites at PhosphoSitePlus (Q02413)
Glycosylation from GlyGen (Q02413) 4 sites, 1 O-linked glycan (1 site)
- Protein Refseq
- NP_001933.2
- Function
- Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "DSG1"
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-786-sdAb | Recombinant Anti-Human DSG1 VHH Single Domain Antibody | IP, ChiP, IHC, ELISA | Llama VHH |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1095z | Mouse Anti-DSG1 Recombinant Antibody (clone 7A12) | WB, IP, IF, IHC | Mouse IgG1, κ |
| MOB-1095MZ | Recombinant Mouse Anti-Human DSG1 Antibody (clone 38C3) | ICC/IF, IP WB | Mouse antibody |
| FAMAB-0206-CN | Human Anti-DSG1 Recombinant Antibody (clone (D31)2/28) | ELISA, IF, IB | Human IgG |
| FAMAB-0207-CN | Human Anti-DSG1 Recombinant Antibody (clone (D31)12a/5) | ELISA, IF, IB | Human IgG |
| MRO-0497-CN | Rabbit Anti-DSG1 Recombinant Antibody (clone JB19-46) | WB, IHC | Rabbit IgG |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0319CL | Human Anti-DSG1 Recombinant Antibody (TAB-0319CL) | ELISA, IF, IP | Human IgG |
| TAB-0319CL-F(E) | Human Anti-DSG1 Recombinant Antibody; Fab Fragment (TAB-0319CL-F(E)) | ELISA, IF, IP | Human Fab |
| TAB-257MZ | Human Anti-DSG1 Recombinant Antibody (TAB-257MZ) | ELISA, Inhib | Human IgG |
| TAB-257MZ-S(P) | Human Anti-DSG1 Recombinant Antibody; scFv Fragment (TAB-257MZ-S(P)) | ELISA | Human scFv |
| TAB-257MZ-F(E) | Human Anti-DSG1 Recombinant Antibody; Fab Fragment (TAB-257MZ-F(E)) | ELISA | Human Fab |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1053 | Hi-Affi™ Rabbit Anti-DSG1 Recombinant Antibody (clone DS1053AB) | WB | Rabbit IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0206-CN-S(P) | Human Anti-DSG1 Recombinant Antibody (clone (D31)2/28); scFv Fragment | ELISA, IF, IB | Human scFv |
| FAMAB-0207-CN-S(P) | Human Anti-DSG1 Recombinant Antibody (clone (D31)12a/5); scFv Fragment | ELISA, IF, IB | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0206-CN-F(E) | Human Anti-DSG1 Recombinant Antibody (clone (D31)2/28); Fab Fragment | ELISA, IF, IB | Human Fab |
| FAMAB-0207-CN-F(E) | Human Anti-DSG1 Recombinant Antibody (clone (D31)12a/5); Fab Fragment | ELISA, IF, IB | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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