Rabbit Anti-DUSP1 Recombinant Antibody (clone R03-5D1) (CAT#: VS3-XY3339)
It is a recombinant rabbit antibody that recognizes human DUSP1 (Dual specificity phosphatase 1). It is capable of recognizing human, mouse and rat DUSP1. It has been used in a variety of applications, such as Western Blot, Immunohistochemistry-Paraffin, Immunoprecipitation, Flow cytometry, Immunocytochemistry or Immunofluorescence.
Specific Inquiry
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line SiHa
(Immunofluorescent staining of human cell line SiHa shows localization to nucleoli & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69577/1586_C7_2_selected.jpg
(Immunofluorescent staining of human cell line SiHa shows localization to nucleoli & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69577/1586_C7_2_selected.jpg
Figure 2 RNA cell line category: Cell line enhanced (HHSteC, hTCEpi, REH)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000120129-DUSP1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000120129-DUSP1
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat DUSP1
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R03-5D1
- Applications
- WB, IHC-P, ICC, IF, IP, FC
- Related Disease
- Intellectual Developmental Disorder, X-Linked 108; Ovarian Cancer
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IHC: 1/50-1/100
IF: 1/50-1/200
IP: 1/20
FC: 1/50-1/100
Target
- Alternative Names
- HVH1; MKP1; CL100; MKP-1; PTPN10
- Gene ID
- 1843
- UniProt ID
- P28562
- Long Name
- Dual specificity phosphatase 1
- Cellular Localization
- Nucleus
- Post Translation Modifications
- Phosphorylation at Ser-359 and Ser-364 by MAPK1/ERK2 and MAPK3/ERK1 reduces its rate of degradation. (P28562-DUS1_HUMAN)
Ubiquitination at Lys280 (NX_P28562 [NX_P28562-1])
Modification sites at PhosphoSitePlus
- Protein Refseq
- NP_004408.1
- Function
- Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185', regulating its activity during the meiotic cell cycle.
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "DUSP1"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3320z | Mouse Anti-DUSP1 Recombinant Antibody (clone 31A1) | WB, ELISA, ICC, IF | Mouse IgG2b, κ |
| MRO-0498-CN | Rabbit Anti-DUSP1 Recombinant Antibody (clone CBACN-202) | WB, IHC, IP, FC | Rabbit IgG |
| VS3-CJ846 | Rabbit Anti-DUSP1 Recombinant Antibody (VS3-CJ846) | WB, IHC, IP, FC | Rabbit IgG |
MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0219 | APC-A*02:01/Human CL100 (QQFPGTAPKL) MHC Tetramer | FCM | |
| MHC-CN0220 | PE-A*02:01/Human CL100 (QQFPGTAPKL) MHC Tetramer | FCM |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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