Human Anti-F11 Recombinant Antibody (HPAB-N0087-YC) (CAT#: HPAB-N0087-YC)
This humanized recombinant antibody specifically bind to the Coagulation Factor XI (FXIa/F11) of human. The monoclonal antibody was generated and isolated with the phage display technology. The specificity and affinity of the product to FXIa was identified and characterized with the neutralization assay and competitive binding assay by ELISA with the EC₅₀ value of 0.2 nM. This antibody could Inhibit the FXIIa induced conversion of FXI into its active form FXIa with the IC₅₀ value of 5.98×10-10 M. The product could be used in research studies about thrombotic diseases.
Specific Inquiry
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line Hep G2
(Immunofluorescent staining of human cell line Hep G2 shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/39808/1663_A5_1_selected.jpg
(Immunofluorescent staining of human cell line Hep G2 shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/39808/1663_A5_1_selected.jpg
Figure 2 RNA cell line category: Cell line enriched (Hep G2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000088926-F11
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000088926-F11
Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized IgG
- Specificity
- Human F11
- Species Reactivity
- Human
- Applications
- ELISA, Inhib
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Coagulation Factor XI; Plasma Thromboplastin Antecedent; FXI; PTA; EC 3.4.21.27; EC 3.4.21
- Gene ID
- 2160
- UniProt ID
- P03951
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "F11"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-342 | Recombinant Anti-human F11 Antibody | ELISA, WB, IF, FuncS | IgG |
| MHH-342 | Recombinant Human Anti-human F11 Antibody | WB, IF, FuncS | IgG |
| MOB-1613MZ | Recombinant Mouse Anti-Human F11 Antibody (clone NN0204-8D49) | Neut, WB | Mouse antibody |
| HPAB-M0518-YC | Mouse Anti-F11 Recombinant Antibody (HPAB-M0518-YC) | ELISA, Inhib | Mouse IgG |
| PABJ-0154 | Human Anti-F11 Recombinant Antibody (clone MAA868) | Inhib, FuncS | Human IgG |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-018WM | Mouse Anti-F11 Recombinant Antibody (TAB-018WM) | Inhib, ELISA | Mouse IgG, κ |
| TAB-018WM-S(P) | Mouse Anti-F11 Recombinant Antibody; scFv Fragment (TAB-018WM-S(P)) | Inhib, ELISA | Mouse scFv |
| TAB-020WM-S(P) | Mouse Anti-F11 Recombinant Antibody; scFv Fragment (TAB-020WM-S(P)) | WB | Mouse scFv |
| TAB-018WM-F(E) | Mouse Anti-F11 Recombinant Antibody; Fab Fragment (TAB-018WM-F(E)) | Inhib, ELISA | Mouse Fab |
| TAB-020WM-F(E) | Mouse Anti-F11 Recombinant Antibody; Fab Fragment (TAB-020WM-F(E)) | WB | Mouse Fab |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-019WM | Human Anti-F11 Recombinant Antibody (TAB-019WM) | Inhib, ELISA, FC | Human IgG |
| TAB-019WM-S(P) | Human Anti-F11 Recombinant Antibody; scFv Fragment (TAB-019WM-S(P)) | Inhib, ELISA, FC | Human scFv |
| TAB-019WM-F(E) | Human Anti-F11 Recombinant Antibody; Fab Fragment (TAB-019WM-F(E)) | Inhib, ELISA, FC | Human Fab |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-754CQ | Mouse Anti-F11 Recombinant Antibody (VMC179) | WB, IP, Neut | Mouse IgG2b |
| NEUT-755CQ | Mouse Anti-F11 Recombinant Antibody (clone CBL028) | Neut, WB | Mouse IgG2 |
| NEUT-756CQ | Mouse Anti-F11 Recombinant Antibody (clone MM0193-7C38) | WB, Neut | Mouse IgG2 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4164 | Hi-Affi™ Rabbit Anti-F11 Recombinant Antibody (clone SI241DS) | ELISA | Rabbit IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0518-YC-F(E) | Mouse Anti-F11 Recombinant Antibody; Fab Fragment (HPAB-M0518-YC-F(E)) | ELISA, Inhib | Mouse Fab |
| HPAB-M0519-YC-F(E) | Human Anti-F11 Recombinant Antibody; Fab Fragment (HPAB-M0519-YC-F(E)) | ELISA | Humanized Fab |
| HPAB-M0520-YC-F(E) | Human Anti-F11 Recombinant Antibody; Fab Fragment (HPAB-M0520-YC-F(E)) | ELISA, Inhib | Humanized Fab |
| HPAB-M0521-YC-F(E) | Human Anti-F11 Recombinant Antibody; Fab Fragment (HPAB-M0521-YC-F(E)) | ELISA, Inhib | Humanized Fab |
| HPAB-2250LY-F(E) | Mouse Anti-F11 Recombinant Antibody; Fab Fragment (HPAB-2250LY-F(E)) | ELISA | Mouse Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2244LY-S(P) | Mouse Anti-F11 Recombinant Antibody; scFv Fragment (HPAB-2244LY-S(P)) | ELISA | Mouse scFv |
| HPAB-N0087-YC-S(P) | Human Anti-F11 Recombinant Antibody; scFv Fragment (HPAB-N0087-YC-S(P)) | ELISA, Inhib | Humanized scFv |
| HPAB-0666YY-S(P) | Human Anti-F11 Recombinant Antibody; scFv Fragment (HPAB-0666YY-S(P)) | ELISA, FuncS | Human scFv |
| PABJ-0081-S(P) | Human Anti-F11 Recombinant Antibody (clone 1213790); scFv Fragment | ELISA, Inhib | Human scFv |
| PABJ-0154-S(P) | Human Anti-F11 Recombinant Antibody (clone MAA868); scFv Fragment | Inhib, FuncS | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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