Rabbit Anti-FABP1 Recombinant Antibody (clone R02-3K2) (CAT#: VS3-XY3353)
The rabbit recombinant antibody specifically binds to human FABP1 (Fatty acid binding protein 1), which plays a role in lipoprotein-mediated cholesterol uptake in hepatocytes. FABP1 may be involved in intracellular lipid transport. The antibody also has cross-reactivity against mouse FABP1. It has been detected using Western Blot and Flow cytometry.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line CACO-2
(Immunofluorescent staining of human cell line CACO-2 shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28275/1030_E2_6_selected.jpg
(Immunofluorescent staining of human cell line CACO-2 shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28275/1030_E2_6_selected.jpg
Figure 2 Duodenum
(Endocrine cells Staining: Medium Intensity: Moderate Enterocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Enterocytes - Gradient Gradient: Ascending Enterocytes - Microvilli Staining: Medium Intensity: Moderate Glands of Goblet cells Staining: Medium Intensity: Moderate Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28275/60872_A_9_2.jpg
(Endocrine cells Staining: Medium Intensity: Moderate Enterocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Enterocytes - Gradient Gradient: Ascending Enterocytes - Microvilli Staining: Medium Intensity: Moderate Glands of Goblet cells Staining: Medium Intensity: Moderate Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28275/60872_A_9_2.jpg
Figure 3 Colon
(Endocrine cells Staining: High Intensity: Strong Enterocytes Staining: High Intensity: Strong Quantity: 75%-25% Enterocytes - Gradient Gradient: Ascending Enterocytes - Microvilli Staining: High Intensity: Strong Goblet cells Staining: High Intensity: Strong Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28275/60872_A_9_3.jpg
(Endocrine cells Staining: High Intensity: Strong Enterocytes Staining: High Intensity: Strong Quantity: 75%-25% Enterocytes - Gradient Gradient: Ascending Enterocytes - Microvilli Staining: High Intensity: Strong Goblet cells Staining: High Intensity: Strong Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28275/60872_A_9_3.jpg
Figure 4 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28275/60872_A_7_4.jpg
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28275/60872_A_7_4.jpg
Figure 5 RNA cell line category: Group enriched (CACO-2, Hep G2)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000163586-FABP1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000163586-FABP1
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human and Mouse FABP1
- Species Reactivity
- Human, Mouse
- Clone
- R02-3K2
- Applications
- WB, FC
- Related Disease
- Hepatocellular Adenoma; Type 1 Diabetes Mellitus 19
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
FC: 1/50-1/100
Target
- Alternative Names
- FABPL; L-FABP
- Gene ID
- 2168
- UniProt ID
- P07148
- Long Name
- Fatty acid binding protein 1
- Cellular Localization
- Cytoplasm
- Post Translation Modifications
- Modification sites at PhosphoSitePlus (P07148)
Modification sites at neXtProt (NX_P07148)
Glycosylation from GlyGen (P07148) 1 site, 1 O-linked glycan (1 site)
- Protein Refseq
- XP_054197003.1; NP_001434.1
- Function
- Plays a role in lipoprotein-mediated cholesterol uptake in hepatocytes (PubMed:25732850).
Binds cholesterol (PubMed:25732850).
Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm.
May be involved in intracellular lipid transport (By similarity).
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "FABP1"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1252MZ | Recombinant Mouse Anti-Human FABP1 Antibody (clone 3H5) | ELISA, IHC-P, WB | Mouse antibody |
| ZG-016R | Mouse Anti-FABP1 Recombinant Antibody (ZG-016R) | ELISA | Mouse IgG |
| ZG-017R | Mouse Anti-FABP1 Recombinant Antibody (ZG-017R) | ELISA | Mouse IgG |
| VS3-QX399 | Mouse Anti-FABP1 Recombinant Antibody (clone 2D6-F6) | ELISA | Mouse IgG1 |
| VS3-FY531 | Recombinant Rabbit Anti-FABP1 Antibody (clone R08-7J1) | WB, IHC-Fr, IHC-P, ICC, IF | Rabbit IgG |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0200MZ | Chicken Anti-FABP1 Polyclonal IgY | WB | Chicken antibody |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1232 | Hi-Affi™ Rabbit Anti-FABP1 Recombinant Antibody (clone DS1232AB) | WB, FC | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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