Rabbit Anti-FKBP6 Recombinant Antibody (clone R05-4G2) (CAT#: VS3-FY2005)

The R05-4G2 recombinant monoclonal antibody detects human FKBP6. It cross-reacts with mouse, rat. It is suitable for use in a variety of assays, including WB, IHC-P. The specificity of the FKBP6 antibody was confirmed by western blot analysis of FKBP6 in rat brain, 3T3, mouse brain, mouse lung lysates and western blot analysis of FKBP6 in Hela, A549, HL-60, U251, U87-MG lysates using FKBP6 antibody.


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WB

Figure 1 Anti-FKBP6 Antibody (VS3-FY2005) in WB.

Figure 1 Anti-FKBP6 Antibody (VS3-FY2005) in WB.

The FKBP6 expression in rat brain, 3T3, mouse brain, mouse lung lysates were detected using the anti-FKBP6 by western blot assay.

WB

Figure 2 Anti-FKBP6 Antibody (VS3-FY2005) in WB.

Figure 2 Anti-FKBP6 Antibody (VS3-FY2005) in WB.

The FKBP6 expression in Hela, A549, HL-60, U251, U87-MG lysates were detected using the anti-FKBP6 by western blot assay.


Specifications

  • Immunogen
  • Synthetic peptide of human FKBP6
  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human, Mouse and Rat FKBP6
  • Species Reactivity
  • Human, Mouse, Rat
  • Clone
  • R05-4G2
  • Applications
  • Western Blot, Immunohistochemistry-Paraffin
  • MW
  • The calculated weight of the target protein is approximately 37 kDa, while the observed molecular weight stands at 37 kDa.
  • Related Disease
  • Spermatogenic Failure 77 and Male Infertility

Product Property

  • Purification
  • Affinity Purified
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% glycerol, 0.05% BSA
  • Preservative
  • 0.01% Sodium azide
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • Western Blot: 1/500-1/1000
    Immunohistochemistry: 1/50-1/100

Target

  • Alternative Names
  • FK506 Binding Protein 6; Immunophilin FKBP36; FK506 Binding Protein 6, 36kDa; Inactive PPIase FKBP6; 36 KDa FKBP; Rotamase; FKBP36; Inactive Peptidyl-Prolyl Cis-Trans Isomerase FKBP6; Peptidyl-Prolyl Cis-Trans Isomerase FKBP6
  • Sequence Similarities
  • Belongs to the FKBP6 family.
  • Cellular Localization
  • Cytoplasm, Nucleus
  • Post Translation Modifications
  • Modification sites at PhosphoSitePlus (O75344)
    Modification sites at neXtProt (NX_O75344)
  • Function
  • Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons (By similarity).
    Acts as a co-chaperone via its interaction with HSP90 and is required for the piRNA amplification process, the secondary piRNA biogenesis (By similarity).

Recommended Products

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "FKBP6"

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1312 Hi-Affi™ Rabbit Anti-FKBP6 Recombinant Antibody (clone DS1312AB) WB, IHC, FC Rabbit IgG

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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