Recombinant Human Anti-gB Antibody (I2-1) (CAT#: FAMAB-0118YC)
In the case of humoral immunity, epitopes, in particular antigenic domain-1, in glycoprotein B have proven to be important for the induction of virus-neutralizing activity. Such antibodies can exert potent virus-neutralizing activity but can also block neutralizing antibodies from binding. The clone I2-1 displayed neutralizing activity for CMV.
Specific Inquiry
Neut
Figure 2 Neutralization potential of scFv variants as a function of immunoreactivity.
The titer of 31 dimerized preparations giving rise to a 50% reduction of input infectivity with CMV strain AD169 is shown as a function of their recognition of AD-1 as determined by ELISA.
Specifications
- Host Species
- Human
- Derivation
- Combinatorial library
- Type
- Human IgG
- Specificity
- CMV gB
- Species Reactivity
- CMV
- Clone
- I2-1
- Applications
- ELISA, Western Blot
- Related Disease
- CMV infection
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- Store at -20°C for long-term storage. Avoid freeze/thaw cycles.
Target
- Alternative Names
- Cucumber mosaic virus; CMV
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone I2-1"
See other products for "gB"
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-114 | Recombinant Human Anti-HCMV glycoprotein B Antibody scFv Fragment (1G2 ) | WB, ELISA, Neut, FuncS | scFv |
| PSBL-115 | Recombinant Human Anti-HCMV Glycoprotein B Antibody scFv Fragment (KE5) | WB, ELISA, IF, FuncS | scFv |
| PSBL-116 | Recombinant Human Anti-HCMV glycoprotein B Antibody scFv Fragment (SM5-1) | Neut, FuncS | scFv |
| FAMAB-0117-CN-S(P) | Recombinant Mouse Anti-gB Antibody scFv Fragment (HCMV37) | IP | Mouse scFv |
| FAMAB-0118-CN-S(P) | Recombinant Humanized Anti-gB Antibody scFv Fragment (HuHCMV37) | IP | Humanized scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBZ-056 | Recombinant Human Anti-HCMV AD-2S1 epitope of gB Antibody Fab Fragment (8F9) | ELISA, Neut, FACS | |
| PFBW-056 | Recombinant Human Anti-HCMV AD-2S1 epitope of gB Antibody Fab Fragment (M2J1) | ELISA, Neut, FACS | |
| PFBC-057 | Recombinant Human Anti-HCMV AD-2S1 epitope of gB Antibody Fab Fragment (M2J5) | ELISA, Neut, FACS | |
| FAMAB-0118-YC-F(E) | Recombinant Human Anti-gB Antibody Fab Fragment (I2-1) | ELISA, WB | Human Fab |
| FAMAB-0119-YC-F(E) | Recombinant Human Anti-gB Antibody Fab Fragment (S2-3) | ELISA, WB | Human Fab |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0119YC | Recombinant Human Anti-gB Antibody (S2-3) | ELISA, WB | Human IgG |
| FAMAB-0120YC | Recombinant Human Anti-gB Antibody (S2-6) | ELISA, WB | Human IgG |
| FAMAB-0121YC | Recombinant Human Anti-gB Antibody (S2-10) | ELISA, WB | Human IgG |
| FAMAB-0122YC | Recombinant Human Anti-gB Antibody (ITC52) | ELISA, WB | Human IgG |
| FAMAB-0242-CN | Recombinant Chimeric (Mouse/Human) Anti-gB Antibody (CK1) | WB, ELISA | Chimeric (mouse/human) IgG1, Κ |
MHC Tetramer for Virology
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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