Rabbit Anti-GRB7 Recombinant Antibody (clone R03-7M6) (CAT#: VS3-XY3372)

It is a recombinant rabbit antibody specific for GRB7 (Growth factor receptor bound protein 7), which plays a role in the regulation of cell proliferation and cell migration. It specifically targets human, mouse and rat GRB7. This product has been tested using Western Blot and Immunohistochemistry-Paraffin. The recommended dilutions of Western Blot and Immunohistochemistry-Paraffin is 1/500-1/1000 and 1/50-1/100, respectively.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Normal Tissue
RNA Expression

Specifications

  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human, Mouse and Rat GRB7
  • Species Reactivity
  • Human, Mouse, Rat
  • Clone
  • R03-7M6
  • Applications
  • WB, IHC-P
  • Related Disease
  • Breast Cancer; Gastric Cancer

Product Property

  • Clonality
  • Monoclonal
  • Aggregation
  • < 5%
  • Format
  • Liquid
  • Buffer
  • PBS (pH 7.4), 150 mM NaCl and 50% glycerol
  • Preservative
  • 0.02% sodium azide
  • Storage
  • Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Shipping
  • Ice packs

Applications

  • Application Notes
  • WB: 1/500-1/1000
    IHC: 1/50-1/100

Target

  • Alternative Names
  • Growth factor receptor bound protein 7
  • Long Name
  • Growth factor receptor bound protein 7
  • Cellular Localization
  • Cytoplasm, Cell junction, focal adhesion
  • Post Translation Modifications
  • Modification sites at PhosphoSitePlus (Q14451)
    Modification sites at neXtProt (NX_Q14451)
    Glycosylation from GlyGen (Q14451) 1 site, 1 O-linked glycan (1 site)
  • Function
  • Adapter protein that interacts with the cytoplasmic domain of numerous receptor kinases and modulates down-stream signaling.
    Promotes activation of down-stream protein kinases, including STAT3, AKT1, MAPK1 and/or MAPK3.
    Promotes activation of HRAS.
    Plays a role in signal transduction in response to EGF.
    Plays a role in the regulation of cell proliferation and cell migration.
    Plays a role in the assembly and stability of RNA stress granules.

Recommended Products

Recommended Dilution Buffer

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "GRB7"

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1503 Rabbit Anti-GRB7 Recombinant Antibody (clone DS1503AB) WB, IHC-P, ICC Rabbit IgG

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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