Recombinant monoclonal antibody specially binds to HCV E2 envelope protein. This human anti-core protein antibody (9e1) can be widely used in the detection of patients with HCV infection.
Figure 1 E2-specific human mAbs.
Antibody competition study. Numbers indicate percentage of residual binding signals of biotinylated human mAbs in the presence of blocking mAbs, and the extent of competition is highlighted by warmth of color.
Law, M., Maruyama, T., Lewis, J., Giang, E., Tarr, A. W., Stamataki, Z., ... & Ball, J. K. (2008). Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge. Nature medicine, 14(1), 25-27.
Figure 2 WB analysis proteins in the lysate of HEK 293T cells cotransfected with different plasmids.
The immune complexes were analyzed by SDS-10% PAGE under reducing conditions.
Owsianka, A., Tarr, A. W., Juttla, V. S., Lavillette, D., Bartosch, B., Cosset, F. L., ... & Patel, A. H. (2005). Monoclonal antibody AP33 defines a broadly neutralizing epitope on the hepatitis C virus E2 envelope glycoprotein. Journal of virology, 79(17), 11095-11104.
Figure 3 Neutralization of HCVpp infection by anti-E2 antibodies.
Neutralization of HCVpp derived from E1E2 of three different genotype 1a subtypes.
Owsianka, A., Tarr, A. W., Juttla, V. S., Lavillette, D., Bartosch, B., Cosset, F. L., ... & Patel, A. H. (2005). Monoclonal antibody AP33 defines a broadly neutralizing epitope on the hepatitis C virus E2 envelope glycoprotein. Journal of virology, 79(17), 11095-11104.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-446-S(P) | Recombinant Anti-HCV E2 Antibody scFv Fragment | ELISA, IP, FuncS | scFv |
PSBC-282 | Recombinant Human Anti-HCV E2 Antibody scFv Fragment (HC26AM) | ELISA, Neut | Human scFv |
FAMAB-0358JF-S(P) | Human Anti-HCV E2 Recombinant Antibody (clone 9e1); scFv Fragment | ELISA, FuncS | Human scFv |
PSBS-0067 | Human Anti-HCV E2 Recombinant Antibody (Clone HC84-26); scFv Fragment | ELISA, FuncS | Human scFv |
HPAB-1523WJ-S(P) | Human Anti-HCV E2 protein Recombinant Antibody; scFv Fragment (clone A12) | ELISA, WB | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBL-492 | Mouse Anti-HCV E2 Protein Recombinant Antibody; Fab Fragment (PFBL-492) | ELISA, Neut | Mouse Fab |
PFBL-493 | Recombinant Mouse Anti-HCV E2 Antibody Fab Fragment (AP33) | ELISA | Fab |
PFBL-494 | Recombinant Human Anti-HCV E2 Antibody Fab Fragment (AR3C) | Neut | Fab |
PFBL-495 | Recombinant Human Anti-HCV E2 Antibody Fab Fragment (C2) | Neut | Fab |
PFBL-496 | Recombinant Human Anti-HCV E2 Antibody Fab Fragment (HC33.8) | Neut | Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-437LC | Anti-HCV E2 Recombinant Antibody (503) | ELISA | Human antibody |
MRO-438LC | Anti-HCV E2 Recombinant Antibody (108) | ELISA | Human antibody |
MRO-437LC-F(E) | Anti-HCV E2 Recombinant Antibody Fab Fragment (503) | ELISA | Human antibody |
MRO-438LC-F(E) | Anti-HCV E2 Recombinant Antibody Fab Fragment (108) | ELISA | Human antibody |
MRO-467LC-F(E) | Anti-HCV E2 Recombinant Antibody Fab Fragment (7F2) | ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-476LC | Human Anti-HCV E2 Protein Recombinant Antibody (MRO-476LC) | ELISA, Inhib | Chimeric (mouse/human) IgG |
MRO-476LC-S(P) | Mouse Anti-HCV E2 Protein Recombinant Antibody; scFv Fragment (MRO-476LC-S(P)) | ELISA | Mouse scFv |
MRO-476LC-F(E) | Human Anti-HCV E2 Protein Recombinant Antibody; Fab Fragment (MRO-476LC-F(E)) | ELISA | Chimeric (mouse/human) Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-477LC | Human Anti-HCV E2 Protein Recombinant Antibody (MRO-477LC) | ELISA | Humanized IgG1, κ |
MRO-478LC | Human Anti-HCV E2 Protein Recombinant Antibody (MRO-478LC) | ELISA | Humanized IgG1, κ |
MRO-477LC-F(E) | Human Anti-HCV E2 Protein Recombinant Antibody; Fab Fragment (MRO-477LC-F(E)) | ELISA | Humanized Fab |
MRO-478LC-F(E) | Human Anti-HCV E2 Protein Recombinant Antibody; Fab Fragment (MRO-478LC-F(E)) | ELISA | Humanized Fab |
MRO-479LC-F(E) | Human Anti-HCV E2 Protein Recombinant Antibody; Fab Fragment (MRO-479LC-F(E)) | ELISA | Humanized Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-1191LC | Anti-HCV E2 Recombinant Antibody (A10F2) | ELISA, Inhib | Mouse Antibody |
MRO-1192LC | Anti-HCV E2 Recombinant Antibody (H6D3) | ELISA, Inhib, WB | Mouse Antibody |
MRO-1193LC | Anti-HCV E2 Recombinant Antibody (E3D8) | ELISA, Inhib, WB | Mouse Antibody |
MRO-1194LC | Anti-HCV E2 Recombinant Antibody (A7A6H9) | ELISA, Inhib | Mouse Antibody |
MRO-1195LC | Anti-HCV E2 Recombinant Antibody (G9E1) | ELISA, Inhib | Mouse Antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-LC428 | PE-A*24:02/HCV E2 (EYVLLLFLL) MHC Tetramer | FCM | |
MHC-LC429 | APC-A*24:02/HCV E2 (EYVLLLFLL) MHC Tetramer | FCM |
CAT | Product Name | Application | Type |
---|---|---|---|
EPAF-0065LC | Recombinant Mouse Anti-HCV E2 protein Antibody (JS-81) | ELISA | IgG1 |
EPAF-1294LC | Recombinant Human Anti-HCV E2 protein Antibody (4c2) | ELISA |
CAT | Product Name | Application | Type |
---|---|---|---|
PABC-319 | Recombinant Mouse Anti-HCV E2 Antibody (DAO5) | ELISA, FC | Mouse IgG |
HPAB-1125-CN | Recombinant Human Anti-HCV E2 Antibody (MRCT10.1) | WB, ELISA, IF | Human IgG1, κ |
HPAB-1126-CN | Recombinant Human Anti-HCV E2 Antibody (MRCT10.V79) | WB, ELISA, IF | Human IgG1, κ |
HPAB-1127-CN | Recombinant Human Anti-HCV E2 Antibody (MRCT10.V317) | WB, ELISA, IF | Human IgG1, κ |
FAMAB-0174WJ | Human Anti-HCV E2 Recombinant Antibody (clone 212.1.1) | ELISA, WB, Neut | Human IgG1 |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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