Afuco™ Anti-HGF ADCC Recombinant Antibody (Flanvotumab), ADCC Enhanced (CAT#: AFC-TAB-130)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to HGF. Flanvotumab is a human monoclonal antibody designed for the treatment of melanoma.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 IHC staining of human rectum
(Immunohistochemical staining of human rectum shows strong cytoplasmic and membranous positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/40360/ihc_selected.jpg
(Immunohistochemical staining of human rectum shows strong cytoplasmic and membranous positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/40360/ihc_selected.jpg
Figure 2 Cerebral cortex
(Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/40360/92262_B_8_5.jpg
(Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/40360/92262_B_8_5.jpg
Figure 3 Colon
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/40360/92262_A_7_3.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/40360/92262_A_7_3.jpg
Figure 4 Kidney
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/40360/92262_A_7_5.jpg
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/40360/92262_A_7_5.jpg
Figure 5 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/40360/92262_A_5_6.jpg
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/40360/92262_A_5_6.jpg
Figure 6 RNA cell line category: Cell line enhanced (ASC TERT1, HHSteC, HL-60, hTEC/SVTERT24-B, Karpas-707, U-87 MG)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000019991-HGF
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000019991-HGF
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Clone
- Flanvotumab
- Applications
- Neut, ELISA, IF, IP, FuncS, FC
- Conjugate
- Unconjugated
- Generic Name
- Flanvotumab
- Related Disease
- Malignant melanoma
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Flanvotumab; 1188277-05-5; IMC-20D7S; TA99; 20D7; HGF; hepatocyte growth factor (hepapoietin A; scatter factor); deafness, autosomal recessive 39, DFNB39; hepatocyte growth factor; F TCF; fibroblast derived tumor cytotoxic factor; hepatopoietin A; HGFB; HPTA;
- Gene ID
- 3082
- UniProt ID
- P14210
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Flanvotumab"
Anti-Human TYRP1 Recombinant Antibody (Flanvotumab)Recombinant monoclonal antibody to TYRP1. Flanvotumab is a human monoclonal antibody designed for the treatment of melanoma.
See other products for "HGF"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1362z | Mouse Anti-HGF Recombinant Antibody (clone 23C2) | WB, ELISA, FuncS | Mouse IgG1 |
| HPAB-0651-CN | Mouse Anti-HGF Recombinant Antibody (HPAB-0651-CN) | IHC, WB, FC | Mouse IgG1, κ |
| HPAB-0652-CN | Mouse Anti-HGF Recombinant Antibody (HPAB-0652-CN) | ELISA, Neut | Mouse IgG1, κ |
| HPAB-0653-CN | Mouse Anti-HGF Recombinant Antibody (HPAB-0653-CN) | ELISA, Neut | Mouse IgG1, κ |
| HPAB-0654-CN | Mouse Anti-HGF Recombinant Antibody (HPAB-0654-CN) | ELISA, Neut | Mouse IgG1, κ |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-080 | Human Anti-HGF Recombinant Antibody (TAB-080) | WB, ELISA, FC, IP, FuncS, IF, Neut | Human IgG2, κ |
| TAB-076CT | Anti-Human HGF/SF Recombinant Antibody (2C3) | ELISA, WB | Human antibody |
| TAB-076CT-S(P) | Anti-Human HGF/SF Recombinant Antibody scFv Fragment (2C3) | ELISA, WB | Human antibody |
| TAB-076CT-F(E) | Anti-Human HGF/SF Recombinant Antibody Fab Fragment (2C3) | ELISA, WB | Human antibody |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-749 | Anti-HGF Recombinant Antibody (Ficlatuzumab) | ELISA, FC, IP, FuncS, IF, Neut, WB | IgG1 - kappa |
| TAB-075CT | Human Anti-HGF Recombinant Antibody (TAB-075CT) | ELISA, Neut | Humanized antibody |
| TAB-075CT-S(P) | Human Anti-HGF Recombinant Antibody; scFv Fragment (TAB-075CT-S(P)) | ELISA, Neut | Humanized scFv |
| TAB-075CT-F(E) | Human Anti-HGF Recombinant Antibody; Fab Fragment (TAB-075CT-F(E)) | ELISA, Neut | Humanized Fab |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-078CT | Llama Anti-HGF Recombinant Single Domain Antibody (TAB-078CT) | Block | Llama VHH |
| HPAB-0993WJ | Recombinant Camelid Anti-HGF Single Domain Antibody (HGF13) | ELISA | Camelid VHH |
| HPAB-0994WJ | Recombinant Human Anti-HGF Antibody (HGF13hum5) | ELISA | Humanized sdAb |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-900CQ | Mouse Anti-HGF Recombinant Antibody (clone 24612.111) | ELISA, WB, Neut | Mouse IgG1 |
| NEUT-901CQ | Mouse Anti-HGF Recombinant Antibody (clone 5D20) | WB, Neut | Mouse IgG1 |
| NEUT-902CQ | Mouse Anti-HGF Recombinant Antibody (clone CBL070) | Neut, WB | Mouse IgG1 |
| NEUT-903CQ | Mouse Anti-HGF Recombinant Antibody (clone CBL435) | WB, Neut | Mouse IgG1 |
| NEUT-904CQ | Mouse Anti-HGF Recombinant Antibody (clone CBL1017) | Neut | Mouse IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1591 | Rabbit Anti-HGF Recombinant Antibody (clone DS1591AB) | ELISA | Rabbit IgG |
| MOR-4217 | Rabbit Anti-HGF Recombinant Antibody (clone SI296DS) | ELISA | Rabbit IgG |
| MOR-4585 | Rabbit Anti-HGF Recombinant Antibody (clone TH98DS) | WB, IF, ICC, FC | Rabbit IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0651-CN-F(E) | Mouse Anti-HGF Recombinant Antibody; Fab Fragment (HPAB-0651-CN-F(E)) | ELISA, Neut | Mouse Fab |
| HPAB-0652-CN-F(E) | Mouse Anti-HGF Recombinant Antibody; Fab Fragment (HPAB-0652-CN-F(E)) | ELISA, Neut | Mouse Fab |
| HPAB-0653-CN-F(E) | Mouse Anti-HGF Recombinant Antibody; Fab Fragment (HPAB-0653-CN-F(E)) | ELISA, Neut | Mouse Fab |
| HPAB-0654-CN-F(E) | Mouse Anti-HGF Recombinant Antibody; Fab Fragment (HPAB-0654-CN-F(E)) | ELISA, Neut | Mouse Fab |
| HPAB-1858-FY-S(P) | Human Anti-HGF Recombinant Antibody; scFv Fragment (HPAB-1858-FY-S(P)) | ELISA | Human scFv |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-749 | Afuco™ Anti-HGF ADCC Recombinant Antibody (Ficlatuzumab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
| AFC-TAB-080 | Afuco™ Anti-HGF Recombinant Antibody (AFC-TAB-080), ADCC Enhanced | ELISA, FC, IP, FuncS, IF | Human IgG1, κ |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0378-YJ-S(P) | Mouse Anti-HGF Recombinant Antibody (clone L2G7); scFv Fragment | ELISA, Neut, Inhib, FuncS | Mouse scFv |
| HPAB-0380-YJ-S(P) | Human Anti-HGF Recombinant Antibody (clone HuL2G7); scFv Fragment | ELISA, Neut, Inhib, FuncS | Humanized scFv |
| HPAB-0990WJ-S(P) | Human Anti-HGF Recombinant Antibody (clone 2.12.1); scFv Fragment | ELISA | Human scFv |
| HPAB-1857-FY-F(E) | Human Anti-HGF Recombinant Antibody; Fab Fragment (HPAB-1857-FY-F(E)) | ELISA | Human Fab |
| HPAB-1858-FY-F(E) | Human Anti-HGF Recombinant Antibody; Fab Fragment (HPAB-1858-FY-F(E)) | ELISA | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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