Mouse Anti-HIV-1 gp160 Recombinant Antibody (clone 1579) (CAT#: MRO-3823CQ)

Recombinant mouse antibody to gp160(728-745). 1579 neutralized IIIB, but not RF or MN.


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WB

Figure 1 Western blot analysis of HIV-1 antigen-specific antibodies.

Figure 1 Western blot analysis of HIV-1 antigen-specific antibodies.

Sera obtained at week 6.

Montefiori, D. C., Safrit, J. T., Lydy, S. L., Barry, A. P., Bilska, M., Vo, H. T., ... & Rovinski, B. (2001). Induction of neutralizing antibodies and gag-specific cellular immune responses to an R5 primary isolate of human immunodeficiency virus type 1 in rhesus macaques. Journal of virology, 75(13), 5879-5890.

Neut

Figure 2 Neutralization of HIV-1 by sera from immunized animal.

Figure 2 Neutralization of HIV-1 by sera from immunized animal.

Bar height represents the percent reduction in p24 relative to the amount of p24 produced in the presence of the corresponding preimmunization serum from each animal as assayed at a 1:2 dilution.

Montefiori, D. C., Safrit, J. T., Lydy, S. L., Barry, A. P., Bilska, M., Vo, H. T., ... & Rovinski, B. (2001). Induction of neutralizing antibodies and gag-specific cellular immune responses to an R5 primary isolate of human immunodeficiency virus type 1 in rhesus macaques. Journal of virology, 75(13), 5879-5890.


Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse IgG
  • Specificity
  • Recognizes HIV-1 gp160(728-745)
  • Species Reactivity
  • HIV-1
  • Clone
  • 1579
  • Applications
  • WB, Neut

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The HIV-1 gp160 antibody has been reported in applications of Western Blot, Neutralization. WB: Serum samples were assayed at a 1:100 dilution.

Target

  • Alternative Names
  • Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP160; gp160; HIV envelope

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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