Rat Anti-HIV-1 gp160 Recombinant Antibody (clone 38/12b) (CAT#: MRO-4029CQ)

Recombinant Rat Antibody to gp160(172-191). This antibody binds native and deglycosylated gp120. 38/12b, which react with linear V2 region epitopes within residues 172 to 191.


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  • Published Data
  • Datasheet
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  • COA
WB

Figure 1 Multiple glycoforms are also present in the V1/V2 fusion glycoprotein expressed in the absence of most of the murine leukemia virus env carrier
domain.

Figure 1 Multiple glycoforms are also present in the V1/V2 fusion glycoprotein expressed in the absence of most of the murine leukemia virus env carrier domain.

Data are all from at least 3 independent experiments.

Wu, Z., Kayman, S. C., Honnen, W., Revesz, K., Chen, H., Vijh-Warrier, S., ... & Pinter, A. (1995). Characterization of neutralization epitopes in the V2 region of human immunodeficiency virus type 1 gp120: role of glycosylation in the correct folding of the V1/V2 domain. Journal of Virology, 69(4), 2271-2278.


Specifications

  • Host Species
  • Rat
  • Type
  • Rat IgG
  • Specificity
  • Recognizes HIV-1 gp160(172-191)
  • Species Reactivity
  • HIV-1
  • Clone
  • 38/12b
  • Applications
  • WB

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The HIV-1 gp160 antibody has been reported in applications of Western Blot.WB: NIH 3T3 cells expressing the fusion glycoprotein were metabolically
    labelled overnight with 35S-cysteine in the presence of 2 mM MMN, and the
    supernatant was precipitated with MAbs and analyzed on 15% SDS gels under
    reducing conditions. Lanes: 1, 11/4c; 2, 38/12b; 3, 11/68b; 4, 38/66a; 5, 684-238; 6, G3-4; 7, 38.1a (an anti-C4 rat MAb) (negative control); 8, 2M3 (an anti-V3
    mouse MAb) (negative control).

Target

  • Alternative Names
  • Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP160; gp160; HIV envelope

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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