Human Anti-HIV-1 gp160 Recombinant Antibody (clone 41148D) (CAT#: MRO-3692CQ)

Recombinant human antibody to gp160(305-313). 41148D is the V3 region-targeting, neutralizing anti-gp120 mAb exhibiting ADCC activity and having a linear epitope.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Published Data
  • Datasheet
  • MSDS
  • COA
FuncS

Figure 1 Representative ADCC assay results obtained with a panel of human anti-Env MAbs.

Figure 1 Representative ADCC assay results obtained with a panel of human anti-Env MAbs.

CEM.NKR cells were chronically infected with the HIV-1 strainsindicated.

Alsmadi, O., & Tilley, S. A. (1998). Antibody-Dependent Cellular Cytotoxicity Directed against Cells Expressing Human Immunodeficiency Virus Type 1 Envelope of Primary or Laboratory-Adapted Strains by Human and Chimpanzee Monoclonal Antibodies of Different Epitope Specificities. Journal of Virology, 72(1), 286-293.


Specifications

  • Host Species
  • Human
  • Type
  • Human IgG1
  • Specificity
  • Recognizes HIV-1 gp160(305-313)
  • Species Reactivity
  • HIV-1
  • Clone
  • 41148D
  • Applications
  • FuncS

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • This antibody has been reported for use in Function Assay.

Target

  • Alternative Names
  • Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP160; gp160; HIV envelope

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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