Mouse Anti-HIV-1 gp160 Recombinant Antibody (clone D49) (CAT#: MRO-3852CQ)
Recombinant mouse antibody to gp160(592-608). D49 binds to region 597-613: WGCSGKLICTTAVPWNA.
Specific Inquiry
Neut
Figure 1 Binding of neutralizing (b12) and nonneutralizing (D49) antibodies to Env from a subtype C isolate (DU422) with I559P and V570D mutations.
DU422 Env constructs were expressed on the HEK 293T cell surface and probed with different antibodies.
Kesavardhana, S., & Varadarajan, R. (2014). Stabilizing the native trimer of HIV-1 Env by destabilizing the heterodimeric interface of the gp41 postfusion six-helix bundle. Journal of virology, 88(17), 9590-9604.
FC
Figure 2 Env 900 expressing cells were stained with D49 antibody after sCD4 induced gp120 shedding from 901 the cell surface.
MFIs from histograms are plotted as a function of D49 antibody concentration. Error bars indicate the standard deviations obtained from independent experiments.
Kesavardhana, S., & Varadarajan, R. (2014). Stabilizing the native trimer of HIV-1 Env by destabilizing the heterodimeric interface of the gp41 postfusion six-helix bundle. Journal of virology, 88(17), 9590-9604.
WB
Figure 3 Cleavage of disulfide stabilized Envs analysed by western blot analysis.
Equal volumes of total cell lysates from Env transfected cells were transferred to nitrocellulose membrane and probed with rabbit anti-gp120 polyclonal sera.
Kesavardhana, S., & Varadarajan, R. (2014). Stabilizing the native trimer of HIV-1 Env by destabilizing the heterodimeric interface of the gp41 postfusion six-helix bundle. Journal of virology, 88(17), 9590-9604.
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Recognizes HIV-1 gp160(592-608)
- Species Reactivity
- HIV-1
- Clone
- D49
- Applications
- WB, FC, Neut
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The HIV-1 gp160 antibody has been reported in applications of Western Blot, Flow Cytometry, Neutralization.
Target
- Alternative Names
- Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP160; gp160; HIV envelope
- Gene ID
- 155971
- UniProt ID
- P04578
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "Clone D49"
See other products for "HIV-1 gp160"
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-382 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone VRC08); Fab Fragment | Neut, FuncS | Human Fab |
| PSBW-163 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone 268-D); scFv Fragment | ELISA, Neut | Human scFv |
| PSBC-180 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone 2558); scFv Fragment | ELISA, Neut | Human scFv |
| MRO-3896CQ-F(E) | Mouse Anti-HIV-1 gp160 Recombinant Antibody (clone 41-1); Fab Fragment | Neut | Mouse Fab |
| MRO-3897CQ-F(E) | Mouse Anti-HIV-1 gp160 Recombinant Antibody (clone IIIB-V3-21 (V3-21, EVA3048)); Fab Fragment | ELISA | Mouse Fab |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-075LC | Anti-HIV-1 gp160 Recombinant Antibody (24G3) | WB, ELISA | Human antibody |
| MRO-080LC | Anti-HIV-1 gp160 Recombinant Antibody (81C7) | ELISA | Human antibody |
| MRO-091LC | Anti-HIV-1 gp160 Recombinant Antibody (MAb CL1) | ELISA | Human antibody |
| MRO-100LC | Anti-HIV-1 gp160 Recombinant Antibody (N7019b) | ELISA | Human antibody |
| MRO-075LC-F(E) | Anti-HIV-1 gp160 Recombinant Antibody Fab Fragment (24G3) | ELISA | Human antibody |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-086LC | Anti-HIV-1 gp160 Recombinant Antibody (1C1) | ELISA | Mouse antibody |
| MRO-087LC | Anti-HIV-1 gp160 Recombinant Antibody (1H9) | ELISA | Mouse antibody |
| MRO-089LC | Anti-HIV-1 gp160 Recombinant Antibody (2H8) | ELISA | Mouse antibody |
| MRO-086LC-F(E) | Anti-HIV-1 gp160 Recombinant Antibody Fab Fragment (1C1) | ELISA | Mouse antibody |
| MRO-087LC-F(E) | Anti-HIV-1 gp160 Recombinant Antibody Fab Fragment (1H9) | ELISA | Mouse antibody |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-3673CQ | Chimpanzee Anti-HIV-1 gp160 Recombinant Antibody (clone C311E) | FC, FuncS | Chimpanzee IgG1 |
| MRO-3674CQ | Human Anti-HIV-1 gp160 Recombinant Antibody (clone HGN35) | ELISA | Human IgG |
| MRO-3675CQ | Human Anti-HIV-1 gp160 Recombinant Antibody (clone 10-188) | Neut, WB, ELISA | Human IgG |
| MRO-3676CQ | Human Anti-HIV-1 gp160 Recombinant Antibody (clone 10-380) | Neut | Human IgG |
| MRO-3677CQ | Human Anti-HIV-1 gp160 Recombinant Antibody (clone 10J4) | Neut | Human IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-4019CQ-S(P) | Rat Anti-HIV-1 gp160 Recombinant Antibody (clone 11/85b (11/85b/14I/14I)); scFv Fragment | Neut | Rat scFv |
| MRO-4020CQ-S(P) | Rat Anti-HIV-1 gp160 Recombinant Antibody (clone 12b); scFv Fragment | Neut | Rat scFv |
| MRO-4021CQ-S(P) | Rat Anti-HIV-1 gp160 Recombinant Antibody (clone 60b); scFv Fragment | ELISA | Rat scFv |
| MRO-4022CQ-S(P) | Rat Anti-HIV-1 gp160 Recombinant Antibody (clone 74); scFv Fragment | ELISA | Rat scFv |
| MRO-4039CQ-S(P) | Rat Anti-HIV-1 gp160 Recombinant Antibody (clone 6D8); scFv Fragment | ELISA | Rat scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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