Mouse Anti-HIV-1 gp160 Recombinant Antibody (clone P3C8) (CAT#: MRO-3882CQ)

Recombinant mouse antibody to gp160(146-151). P3C8 neutralized SF162 potently but it did not have any heterologous neutralizing activity.


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Neut

Figure 1 Neutralization of tagged SF162 by anti-FLAG and anti-HA MAbs.

Figure 1 Neutralization of tagged SF162 by anti-FLAG and anti-HA MAbs.

The neutralizing potentials of anti-FLAG and anti-HA MAbs against SF162 virions expressing WT or tagged Envs capable of mediating viral entry were evaluated.

Wallace, A., & Stamatatos, L. (2009). Introduction of exogenous epitopes in the variable regions of the human immunodeficiency virus type 1 envelope glycoprotein: effect on viral infectivity and the neutralization phenotype. Journal of virology, 83(16), 7883-7893.

FC

Figure 2 Cell surface staining of Env-expressing cells.

Figure 2 Cell surface staining of Env-expressing cells.

MAb 2G12 was used as a positive control; as a
negative control, we used cells expressing no Env (cells only).

Wallace, A., & Stamatatos, L. (2009). Introduction of exogenous epitopes in the variable regions of the human immunodeficiency virus type 1 envelope glycoprotein: effect on viral infectivity and the neutralization phenotype. Journal of virology, 83(16), 7883-7893.


Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse IgG1, κ
  • Specificity
  • Recognizes HIV-1 gp160(146-151)
  • Species Reactivity
  • HIV-1
  • Clone
  • P3C8
  • Applications
  • FC, Neut

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The HIV-1 gp160 antibody has been reported in applications of Flow Cytometry, Neutralization.

Target

  • Alternative Names
  • Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP160; gp160; HIV envelope

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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